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A sarcomere (Greek σάρξ sarx "flesh", μέρος meros "part") is the smallest functional unit of striated muscle tissue. [1] It is the repeating unit between two Z-lines. Skeletal muscles are composed of tubular muscle cells (called muscle fibers or myofibers) which are formed during embryonic myogenesis .
The sarcolemma (sarco (from sarx) from Greek; flesh, and lemma from Greek; sheath), also called the myolemma, is the cell membrane surrounding a skeletal muscle fibre or a cardiomyocyte.
Sarcoplasm is the cytoplasm of a muscle cell.It is comparable to the cytoplasm of other cells, but it contains unusually large amounts of glycogen (a polymer of glucose), myoglobin, a red-colored protein necessary for binding oxygen molecules that diffuse into muscle fibers, and mitochondria.
The calcium drives the movement of myosin and actin filaments. The sarcomere then shortens which causes the muscle to contract. [3] In the skeletal muscles connected to tendons that pull on bones, the mysia fuses to the periosteum that coats the bone. Contraction of the muscle will transfer to the mysia, then the tendon and the periosteum ...
A diagram of the structure of a myofibril (consisting of many myofilaments in parallel, and sarcomeres in series) Sliding filament model of muscle contraction. The myosin heads form cross bridges with the actin myofilaments; this is where they carry out a 'rowing' action along the actin. When the muscle fibre is relaxed (before contraction ...
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The costamere is a structural-functional component of striated muscle cells [1] which connects the sarcomere of the muscle to the cell membrane (i.e. the sarcolemma). [ 2 ] Costameres are sub-sarcolemmal protein assemblies circumferentially aligned in register with the Z-disk of peripheral myofibrils .
In addition to sarcomere activity, it has been shown that myomesin also plays a role in the assembly of the sarcomere. In order for myomesin to be implemented into the sarcomere, myosin and titin must be present, indicating that myomesin is the last component to be added during assembly of the lattice.