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The AutoAnalyzer is an early example of an automated chemistry analyzer using a special flow technique named "continuous flow analysis (CFA)", invented in 1957 by Leonard Skeggs, PhD and first made by the Technicon Corporation. The first applications were for clinical (medical) analysis.
The best known of Technicon's CFA instruments are the AutoAnalyzer II (introduced 1970), the Sequential Multiple Analyzer (SMA, 1969), and the Sequential Multiple Analyzer with Computer (SMAC, 1974). The Autoanalyzer II (AAII) is the instrument that most EPA methods were written on and reference.
The Hitachi 917 is an automated biochemistry analyser utilise medical laboratories to process biological fluid specimens, such as urine, cerebrospinal fluid, and most commonly, blood. Manufactured by Boehringer Mannheim , the Hitachi 917 is a commonly used routine chemical bichromatic analyser.
Celloscope automated cell counter was developed in the 50s for enumeration of erythrocytes, leukocytes, and thrombocytes in blood samples. [1] Together with the Coulter counter, the Celloscope analyzer can be considered one of the predecessors of today's automated hematology analyzers, as the principle of the electrical impedance method is still utilized in cell counters installed in clinical ...
His Robot Chemist "was the first commercially available discrete analyzer, and probably the first to produce results with a digital print-out." [ 1 ] Automatic discrete analysis instrumentation revolutionized the field of clinical chemistry, and, eventually, the practice of medicine, as well.
The FIDA principle is based on measuring the change in the apparent size (diffusivity) of a selective indicator interacting with the analyte molecule. [ 1 ] [ 2 ] [ 4 ] The apparent indicator size is measured by Taylor dispersion analysis in a capillary under hydrodynamic flow.
A clinical chemistry analyzer; hand shows size. Clinical chemistry (also known as chemical pathology, clinical biochemistry or medical biochemistry) is a division in medical laboratory sciences focusing on qualitative tests of important compounds, referred to as analytes or markers, in bodily fluids and tissues using analytical techniques and specialized instruments. [1]
As an analytical biochemistry assay and a "wet lab" technique, ELISA involves detection of an analyte (i.e., the specific substance whose presence is being quantitatively or qualitatively analyzed) in a liquid sample by a method that continues to use liquid reagents during the analysis (i.e., controlled sequence of biochemical reactions that will generate a signal which can be easily ...