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[a] Its main current use in pharmacology is treating molluscum contagiosum and warts topically. [2] It is a burn agent and poisonous in large doses, and has been historically used as aphrodisiacs (Spanish fly). In its natural form, cantharidin is secreted by the male blister beetle, and given to the female as a copulatory gift during mating.
Molluscum contagiosum (MC), sometimes called water warts, is a viral infection of the skin that results in small raised pink lesions with a dimple in the center. [1] They may become itchy or sore, and occur singularly or in groups. [1] Any area of the skin may be affected, with abdomen, legs, arms, neck, genital area, and face being the most ...
Warts are usually harmless, but they can be an eyesore. A dermatologist lays out some solutions.
Cantharidin, a poisonous chemical that causes blistering of the skin, is secreted as a defensive agent. It is used medically to remove warts [ 2 ] and is collected for this purpose from species of the genera Mylabris and Lytta , especially Lytta vesicatoria , better known as "Spanish fly".
Per Dr. Thosani, salicylic acid works to "mildly irritate the skin and trigger the immune system to fight the virus," and when applied topically, it can peel off the skin of the wart in layers.
Thompson does not recommend using salicylic acid on the face due to the risk of scarring the delicate skin there. One approach to treating a wart on the face is with immunotherapy, Bunick says.
This beetle is also considered beneficial because cantharidin is used in the medical field as a topical medication in the removal of warts, removal of tattoos, and has even been looked into for certain cancer treatments. [13] Its use in the treatment of removing warts has been common for many years, and is still used by dermatologists.
After skin comes in contact with cantharidin, local irritation begins within a few hours. [3] ( This is in contrast to Paederus dermatitis, where symptoms first appear 12–36 hours after contact with rove beetles.) [4] Painful blisters appear, but scarring from these epidermal lesions is rare.
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