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2. Prostate-specific antigen - Wikipedia

   en.wikipedia.org/wiki/Prostate-specific_antigen

   PSA level is one of three variables on which the risk stratification is based; the others are the grade of prostate cancer (Gleason grading system) and the stage of cancer based on physical examination and imaging studies. D'Amico criteria for each risk category are: [17] Low risk: PSA < 10, Gleason score ≤ 6, AND clinical stage ≤ T2a

3. Gleason grading system - Wikipedia

   en.wikipedia.org/wiki/Gleason_grading_system

   [10] However, problematic aspects of the original Gleason grading system still characterize the 2005 revision. The predominant lowest score assigned is Gleason 3+3 = 6. Patients who are told their Gleason score is 6 out of 10 may interpret that they have a more aggressive intermediate cancer and experience greater anxiety. [11]

4. Prostate cancer staging - Wikipedia

   en.wikipedia.org/wiki/Prostate_cancer_staging

   Of note, this system of describing tumors as "well-", "moderately-", and "poorly-" differentiated based on Gleason score of 2–4, 5–6, and 7–10, respectively, persists in SEER and other databases but is generally outdated. In recent years pathologists rarely assign a tumor a grade less than 3, particularly in biopsy tissue.

5. What Your PSA Test Says About Your Prostate - AOL

   www.aol.com/psa-test-says-prostate-110000368.html

   A PSA of 4 nanograms per milliliter (ng/mL) is typically the cutoff that doctors use to recommend more testing, according to the American Cancer Society. If your levels are between 4 ng/mL and 10 ...

6. Active surveillance of prostate cancer - Wikipedia

   en.wikipedia.org/wiki/Active_surveillance_of...

   The PSA era Prostate Cancer Intervention versus Observation Trial (PIVOT), compared radical prostatectomy to watchful waiting among 731 men (mean age 67 years) with localized prostate cancer. [10] At 12 years, a subset of men with a PSA above 10 ng/ml and those with intermediate to high risk disease had a reduction in prostate cancer death with ...

7. Prostate cancer - Wikipedia

   en.wikipedia.org/wiki/Prostate_cancer

   Those with elevated PSA may undergo secondary screening blood tests that measure subtypes of PSA and other molecules to better predict the likelihood that a person will develop aggressive prostate cancer. Many measure "free PSA" – the fraction of PSA unbound to other blood proteins, usually around 10% to 30%.