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The sweat test measures the concentration of chloride that is excreted in sweat. It is used to screen for cystic fibrosis (CF). [ 1 ] Due to defective chloride channels ( CFTR ), the concentration of chloride in sweat is elevated in individuals with CF.
The first commercially adopted use for sweat diagnostics included testing of sodium and chloride levels in children for the diagnosis of cystic fibrosis. Today, one of the most popular devices for this testing is the Macroduct Sweat Collection System from ELITechGroup. [11]
However, sweat as a diagnostic fluid presents numerous challenges as well, such as very small sample volumes and filtration (dilution) of larger-sized hydrophilic analytes. Currently the only major commercial application for sweat diagnostics is for infant cystic fibrosis testing based on sweat chloride concentrations. [citation needed]
In sweat glands, defective CFTR results in reduced transport of sodium chloride and sodium thiocyanate [21] in the resorptive duct and therefore saltier sweat. This is the basis of a clinically important sweat test for cystic fibrosis often used diagnostically with genetic screening. [22]
Hyperchloremia is an electrolyte disturbance in which there is an elevated level of chloride ions in the blood. [1] The normal serum range for chloride is 96 to 106 mEq/L, [2] therefore chloride levels at or above 110 mEq/L usually indicate kidney dysfunction as it is a regulator of chloride concentration. [3]
Certain Dri prioritizes keeping you sweat-free over all else. Its formula uses aluminum chloride, which is the most powerful of the aluminum salts found in many prescription antiperspirants ...
Whether you need sweat and stink antiperspirant stomping protection, or an aluminum-free odor blocking deodorant, we've got your and your pits covered The 12 best deodorants and antiperspirants ...
To help combat sweat and odor, Saltair uses zinc ricinoleate and tapioca starch rather than harsh ingredients like baking soda or alcohol, so it’s safe for all skin types.
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