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Rothberg estimated the cost of the sequence—the first personal genome produced using a next-generation sequencing platform—at $1 million. [12] Watson's genome sequence was published in 2008. [13] A number of scientists have highlighted the cost of additional analysis after performing sequencing.
The cost must also take into account personnel costs, data processing costs, legal, communications and other costs. One way to assess this is via commercial offerings. The first such whole diploid genome sequencing (6 billion bp, 3 billion from each parent) was from Knome and their price dropped from $350,000 in 2008 to $99,000 in 2009.
Veritas Genetics is a personal genomics startup based in Danvers, Massachusetts. [1] According to the company's press release, it was among the first companies to offer whole genome sequencing and interpretation for under $1,000. [2] It was co-founded in 2014 by George M. Church, Mirza Cifric, Preston Estep, and Jonathan Zhao. [3]
The chemistry will also improve sequencing performance, providing a 33% increase in sequencing yield per SMRT Cell. Collectively, these enhancements will enable each Revio instrument to sequence up to 2,500 human whole genomes per year at a cost of just under $500 per human genome.
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Time Magazine named 23andMe's Personal Genome Service its Invention of the Year in 2008. ... The company reduced the cost of its service to $299 in May 2012 and again to $99 later that year.
In June 2009, Illumina announced that they were launching their own Personal Full Genome Sequencing Service at a depth of 30× for $48,000 per genome. [60] [61] In August, the founder of Helicos Biosciences, Stephen Quake, stated that using the company's Single Molecule Sequencer he sequenced his own full genome for less than $50,000. [62]
Genome sequencing became more cost-effective over time, and made it applicable in the medical field, allowing scientists to understand which genes are attributed to specific diseases. Personalized medicine is an emerging practice in medicine that develops patient-specific treatments based on an individual's genetic profile.
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