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Lipoproteins released from treatment of Treponema pallidum infections are believed to induce the Jarisch–Herxheimer reaction. [3] The Herxheimer reaction has shown an increase in inflammatory cytokines during the period of exacerbation, including tumor necrosis factor alpha , interleukin-6 and interleukin-8 .
Adolf Jarisch (February 15, 1850 – March 21, 1902) was an dermatologist from the Austro-Hungarian Empire who specialized in the care of venereal disease.The Jarisch-Herxheimer reaction, an inflammatory response that he noted following treatment for syphilis, is partially named after him.
All patients treated with antibiotics should be observed during the first 4 hours of treatment for a Jarisch-Herxheimer reaction, which is a worsening of symptoms characterized by rigors, hypotension, and high fever. [5] The reaction occurs in over 50% of cases and may be difficult to distinguish from a febrile crisis. [5]
An Ohio county is experiencing a pediatric outbreak of pneumonia, including a number of cases of mycoplasma pneumonia, the illness that has driven recent outbreaks among children in Denmark and China.
These can, however, induce a Jarisch–Herxheimer reaction in over half those treated, producing anxiety, diaphoresis, fever, tachycardia and tachypnea with an initial pressor response followed rapidly by hypotension. Recent studies have shown tumor necrosis factor-alpha may be partly responsible for this reaction. [citation needed]
Although the current uptake of cognitive testing among older adults remains low, research suggests that participation would increase if the tests were free, easily accessible and supported by ...
Rates of Mycoplasma pneumonia in all global community-acquired pneumonia (CAP) cases range from 10-15%. [13] [14] The rate of Mycoplasma pneumonia in adults with CAP is estimated to be 15%, and the rate of in children with CAP has been reported at 27.4%. [3] The rates of M. pneumoniae among hospitalized CAP cases are 35% in adults [14] and 24% ...
The Jarisch-Herxheimer reaction, which is the response to the body after endotoxins are released by the death of harmful organisms in the human body, starts usually during the first day of antibiotic treatment. [16] The reaction increases the person's body temperature, decreases the overall blood pressure (both systolic and diastolic levels ...