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The skeletal muscle pump. The skeletal muscle pump or musculovenous pump is a collection of skeletal muscles that aid the heart in the circulation of blood. It is especially important in increasing venous return to the heart, [1] but may also play a role in arterial blood flow.
The absolute refractory period for cardiac contractile muscle lasts approximately 200 ms, and the relative refractory period lasts approximately 50 ms, for a total of 250 ms. This extended period is critical, since the heart muscle must contract to pump blood effectively and the contraction must follow the electrical events.
ACTC1 encodes cardiac muscle alpha actin. [ 5 ] [ 6 ] This isoform differs from the alpha actin that is expressed in skeletal muscle, ACTA1 . Alpha cardiac actin is the major protein of the thin filament in cardiac sarcomeres, which are responsible for muscle contraction and generation of force to support the pump function of the heart.
The heart did not pump blood around, the heart's motion sucked blood in during diastole and the blood moved by the pulsation of the arteries themselves. [93] Galen believed the arterial blood was created by venous blood passing from the left ventricle to the right through 'pores' between the ventricles. [90]
The heart is a muscular organ situated in the mediastinum.It consists of four chambers, four valves, two main arteries (the coronary arteries), and the conduction system. The left and right sides of the heart have different functions: the right side receives de-oxygenated blood through the superior and inferior venae cavae and pumps blood to the lungs through the pulmonary artery, and the left ...
Respiratory pump - Intrapleural pressure decreases during inspiration and abdominal pressure increases, squeezing local abdominal veins, allowing thoracic veins to expand and increase blood flow towards the right atrium. Skeletal muscle pump - In the deep veins of the legs, surrounding muscles squeeze veins and pump blood back towards the heart ...
The heart muscle may become inflamed in a condition called myocarditis, [46] most commonly caused by a viral infection [47] but sometimes caused by the body's own immune system. [48] Heart muscle can also be damaged by drugs such as alcohol, long standing high blood pressure or hypertension, or persistent abnormal heart racing. [49]
The heart is a functional syncytium as opposed to a skeletal muscle syncytium. In a functional syncytium, electrical impulses propagate freely between cells in every direction, so that the myocardium functions as a single contractile unit. This property allows rapid, synchronous depolarization of the myocardium.
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