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Selective beta 1 blockers have been shown to have an array of cardiac common side effects, comprising bradycardia, reduced exercise tolerance, hypotension, atrioventricular block, and heart failure. [4] Regarding non-cardiac side effects, they can cause nausea, headache, fatigue, dry mouth, and dry eyes. [4]
Side effects associated with phentolamine include headache, flushing, and nasal congestion. [23] Benign prostate hyperplasia, a disease in which urinary retention becomes an issue. Alpha-1 blockers can be used, but it can result in side effects such as increased urination and retrograde ejaculation.
However, the serotonin receptor antagonism has side effects such as weight gain and impaired movement. [11] Hence, alpha-2 blockers are not used clinically due to its extensive binding. Similar to the alpha-1 blocker, the alpha-2 family will also present the first-dose effect, but it is generally less pronounced compared with the alpha-1 ...
They are mainly used in research, having found limited clinical application in human medicine. They are extensively used in veterinary medicine to reverse the effects of alpha-2 agonist drugs used as sedatives, like xylazine, medetomidine and dexmedetomidine. Alpha-2 blockers increase noradrenaline release.
Alpha-adrenergic antagonists are also used for treatment of ureteric stones, pain and panic disorders, withdrawal, and anesthesia. [ 18 ] [ 2 ] Adrenergic antagonists are used to treat acute cardiovascular toxicity (e.g. in overdose ) caused by sympathomimetics , for instance caused by amphetamine , methamphetamine , cocaine , ephedrine , and ...
It is an α 1 blocker. [6] It is a less preferred treatment of high blood pressure. [6] Other uses may include heart failure and Raynaud syndrome. [7] It is taken by mouth. [6] Common side effects include dizziness, sleepiness, nausea, and heart palpitations. [6] Serious side effects may include low blood pressure with standing and depression.
Alpha-1 blocker, blocks alpha receptors and it relaxes the smooth muscles in the bladder. It helps the urine to flow smoothly and it can lessen the pain caused by the bladder pressing on the prostate. [44] [45] Selective alpha-1 blockers are better tolerated than non-selective alpha blockers in the body and therefore works better on BPH. [2]
Common side effects include dizziness, sleepiness, swelling, nausea, shortness of breath, and abdominal pain. [2] Severe side effects may include low blood pressure with standing, an irregular heart beat, and priapism. [2] [3] It is a selective α 1-adrenergic blocker in the quinazoline class of compounds. [2]