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Poor medical adherence is a common challenge among individuals who have increased pill burden and are subject to polypharmacy. [52] It also increases the possibility of adverse medication reactions (side effects) and drug-drug interactions. High pill burden has also been associated with an increased risk of hospitalization, medication errors ...
This could occur when a patient is given medication that is too strong and is causing detrimental effects or is simply not necessary. [7] Adverse drug reaction. This could occur when a patient has an allergic response to a medication. [7] Inappropriate adherence. This could occur when a patient chooses not to or forgets to take a medication. [7]
Likewise fears of non-adherence also proved to be overblown. Developed countries, when first discussing the implementation of ART in the developing world, believed that the allowance of third-world countries to have early access to antiretroviral drugs would potentially lead to the development of drug resistance.
In medicine, patient compliance (also adherence, capacitance) describes the degree to which a patient correctly follows medical advice.Most commonly, it refers to medication or drug compliance, but it can also apply to other situations such as medical device use, self care, self-directed exercises, or therapy sessions.
HIV drug resistance poses an issue because it reduces the possible HIV medications a person can take due to cross resistance. In cross resistance, an entire class of medication is considered ineffective in lowering a patient's HIV viral load because all the drugs in a given class share the same mechanism of action. [7]
Variations in healthcare provider training & experience [46] [53] and failure to acknowledge the prevalence and seriousness of medical errors also increase the risk. [54] [55] The so-called July effect occurs when new residents arrive at teaching hospitals, causing an increase in medication errors according to a study of data from 1979 to 2006.
Additional barriers transgender women face include concerns about side effects, hormone therapy, adherence, and interaction with healthcare workers. [96] Challenges encountered by people engaging in injection drug use include limited access to healthcare providers, expense of medication, and follow-up for HIV testing. [92]
Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.