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  2. Apremilast - Wikipedia

    en.wikipedia.org/wiki/Apremilast

    Apremilast, sold under the brand name Otezla among others, is a medication for the treatment of certain types of psoriasis and psoriatic arthritis. [4] The drug acts as a selective inhibitor of the enzyme phosphodiesterase 4 (PDE4). [ 4 ]

  3. PDE4 inhibitor - Wikipedia

    en.wikipedia.org/wiki/PDE4_inhibitor

    Apremilast, a phthalimide derivative that was approved by the U.S. FDA in March 2014 for use as a treatment for psoriatic arthritis, [21] and in September 2014 for the treatment of plaque psoriasis under the brand name Otezla. [22] Cilomilast, in clinical development by GlaxoSmithKline for treatment of COPD. [23]

  4. Psoriatic arthritis - Wikipedia

    en.wikipedia.org/wiki/Psoriatic_arthritis

    Psoriatic arthritis (PsA) is a long-term inflammatory arthritis that occurs in people affected by the autoimmune disease psoriasis. [1] [2] The classic features of psoriatic arthritis include dactylitis (sausage-like appearance), skin lesions, and nail lesions. [3]

  5. Amgen Reports Results From Otezla’s Phase 3 Trial For ... - AOL

    www.aol.com/news/amgen-reports-results-otezla...

    Amgen presented results from the Phase 3 ADVANCE trial of Otezla in patients with plaque psoriasis at the American Academy of Dermatology Virtual Meeting Experience 2021. In the placebo-controlled ...

  6. Race to Effective Psoriasis Treatment: Can-Fite's ... - AOL

    www.aol.com/news/race-effective-psoriasis...

    Photo by Christina Victoria Craft on Unsplash The following post was written and/or published as a collaboration between Benzinga’s in-house sponsored content team and a financial partner of ...

  7. Biological response modifier - Wikipedia

    en.wikipedia.org/wiki/Biological_response_modifier

    [4] [9] Adverse effects may be class-dependent, and so switching to a biologic of another class may ameliorate those effects. [ 7 ] Potential serious adverse effects include allergic reactions , liver damage, cancer, and serious infections including tuberculosis , pneumonia , staph infection , and fungal infection .

  8. Bristol Myers' Psoriasis Med Deucravacitinib Superior To ...

    www.aol.com/news/bristol-myers-psoriasis-med...

    Bristol-Myers Squibb Co (NYSE: BMY) has announced new data from its two Phase 3 trials POETYK PSO-1 and POETYK PSO-2 for deucravacitinib, its oral, selective TYK2 inhibitor for moderate to severe ...

  9. Psoriasis - Wikipedia

    en.wikipedia.org/wiki/Psoriasis

    The most common short-term side effect of this form of phototherapy is redness of the skin; less common side effects of NB-UVB phototherapy are itching and blistering of the treated skin, irritation of the eyes in the form of conjunctival inflammation or inflammation of the cornea, or cold sores due to reactivation of the herpes simplex virus ...

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