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The area under the effect curve (AUEC) is an integral of the effect of a drug over time, estimated as a previously-established function of concentration. It was proposed to be used instead of AUC in animal-to-human dose translation, as computer simulation shows that it could cope better with half-life and dosing schedule variations than AUC.
This is a list of abbreviations used in medical prescriptions, including hospital orders (the patient-directed part of which is referred to as sig codes).This list does not include abbreviations for pharmaceuticals or drug name suffixes such as CD, CR, ER, XT (See Time release technology § List of abbreviations for those).
However, if a delay is observed between the drug administration and the drug effect, a temporal dissociation needs to be taken into account and more complex models exist: [6] [7] Direct vs Indirect link PK/PD models; Direct vs Indirect response PK/PD models [8] Time variant vs time invariant; Cell lifespan models; Complex response models
ADME is the four-letter abbreviation (acronym) for absorption, distribution, metabolism, and excretion, and is mainly used in fields such as pharmacokinetics and pharmacology. The four letter stands for descriptors quantifying how a given drug interacts within body over time.
Clinical Pharmacokinetics is a peer-reviewed medical journal published by Adis International (Springer Nature) that covers topics related to pharmacokinetics.According to the Journal Citation Reports, the journal has a 2023 Impact Factor™ of 4.6 ranked 77 of 277 journals in the Pharmacology & Pharmacy category [Clarivate Analytics]; 2023 CiteScore™ of 8.8 ranked 81 of 272 journals in the ...
The U.S. Food and Drug Administration also has guidance to elucidate dose–response relationships [3] during drug development. Dose response relationships may be used in individuals or in populations. The adage The dose makes the poison reflects how a small amount of a toxin has no significant effect, while a large amount may be fatal. This ...
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy is a monthly peer-reviewed medical journal covering human pharmacology and pharmacotherapy, published by Wiley-Blackwell on behalf of the American College of Clinical Pharmacy, of which it is an official journal.
The IUPHAR/BPS Guide to PHARMACOLOGY is an open-access website, acting as a portal to information on the biological targets of licensed drugs and other small molecules. The Guide to PHARMACOLOGY (with GtoPdb being the standard abbreviation) is developed as a joint venture between the International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Pharmacological Society (BPS).