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A clinical trial testing sertraline (Zoloft) for depression of Alzheimer disease, launched by the NIMH in 2004, was due to be completed in the summer of 2009. [9] [needs update] Sertraline, as per the latest studies has been found to be ineffective in improving cognitive outcomes in patients with Alzheimer's disease. [10]
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. [2] It is the cause of 60–70% of cases of dementia. [2] [15] The most common early symptom is difficulty in remembering recent events. [1]
Psychological therapies for dementia are starting to gain some momentum. [ when? ] Improved clinical assessment in early stages of Alzheimer's disease and other forms of dementia , increased cognitive stimulation of the elderly, and the prescription of drugs to slow cognitive decline have resulted in increased detection in the early stages.
“That finding is not surprising to me, because there are early life, midlife and late-life risk factors for dementia. (For) Alzheimer’s disease, for example, pathology starts in the brain ...
Major depression is more common in medically ill patients who are older than 70 years and hospitalized or institutionalized. Severe or chronic diseases associated with high rates of depression include stroke (30–60%), coronary heart disease (8–44%), cancer (1–40%), Parkinson's disease (40%), Alzheimer's disease (20–40%), and dementia ...
Psychoorganic syndrome (POS), also known as organic psychosyndrome, is a progressive disease comparable to presenile dementia.It consists of psychopathological complex of symptoms that are caused by organic brain disorders that involve a reduction in memory and intellect.
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