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[101] [102] [103] It is widely used in the treatment of acne, excessive hair growth, and hyperandrogenism in women, who have much lower testosterone levels than men. [ 99 ] [ 100 ] Because of its antimineralocorticoid activity, spironolactone has antimineralocorticoid side effects [ 104 ] and can cause high potassium levels .
Gonadorelin is the generic name of the drug and its INN Tooltip International Nonproprietary Name, BAN Tooltip British Approved Name, and JAN Tooltip Japanese Accepted Name, while gonadorelina is its DCIT Tooltip Denominazione Comune Italiana and gonadoréline is its DCF Tooltip Dénomination Commune Française.
Menopur, 5 mL vials containing 75 IU FSH and 75 IU LH. Repronex, vials containing either 75 IU FSH and 75 IU LH, or 150 IU FSH and 150 IU LH. Common side effects of preparations containing FSH and LH are: [4] Mild bloating; Pain, swelling, or irritation injection site; Rash at injection site or other part of body; Stomach pain or pelvic pain
[8] [9] In men, they are being investigated in the treatment of benign prostatic hyperplasia [10] and also as potential contraceptive agents. [11] GnRH antagonists could be used as puberty blockers in transgender youth and to suppress sex hormone levels in transgender adolescents and adults, but have not been studied in this context.
Gender-affirming hormone therapy (GAHT), also called hormone replacement therapy (HRT) or transgender hormone therapy, is a form of hormone therapy in which sex hormones and other hormonal medications are administered to transgender or gender nonconforming individuals for the purpose of more closely aligning their secondary sexual characteristics with their gender identity.
Enclomifene (INN Tooltip International Nonproprietary Name), or enclomiphene (USAN Tooltip United States Adopted Name), a nonsteroidal selective estrogen receptor modulator of the triphenylethylene group, acts by antagonizing the estrogen receptor (ER) in the pituitary gland, which reduces negative feedback by estrogen on the hypothalamic-pituitary-gonadal axis, thereby increasing gonadotropin ...
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They are also sometimes used as alternatives to antiandrogens like spironolactone and cyproterone acetate for suppressing testosterone production in transgender women. [19] [20] [21] It also is used for suppressing estrogen production in transgender men. [22] It is considered a possible treatment for paraphilias. [23]
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