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Medroxyprogesterone acetate (brand names Depo-Provera, Provera, Depo-subQ Provera 104) [4] – 150 mg (intramuscularly) or 104 mg (subcutaneously) every 3 months [3] Norethisterone enanthate (brand names NET EN, Noristerat, Norigest, Doryxas) [5] – 200 mg (intramuscularly) every 2 months [3]
CICs are different from progestogen-only injectable contraceptives (POICs), such as depot medroxyprogesterone acetate (DMPA; brand names Depo-Provera, Depo-SubQ Provera 104) and norethisterone enantate (NETE; brand name Noristerat), which are not combined with an estrogen and are given once every two to three months instead of once a month. [2]
[11] [12] [129] Its most major brand names are Provera as oral tablets and Depo-Provera as an aqueous suspension for intramuscular injection. [11] [12] [129] A formulation of MPA as an aqueous suspension for subcutaneous injection is also available in the United States under the brand name Depo-SubQ Provera 104.
Estradiol cypionate/medroxyprogesterone acetate (EC/MPA), sold under the brand name Cyclofem among others, is a form of combined injectable birth control. [2] It contains estradiol cypionate (EC), an estrogen , and medroxyprogesterone acetate (MPA), a progestin . [ 2 ]
[1] [6] [81] In contrast to depot medroxyprogesterone acetate, no increase in VTE risk has been observed with moderately high doses of the related progestin chlormadinone acetate (10 mg/day for 18–20 days/cycle), though based on limited data. [94] [95]
In the fertility awareness-based method a woman who has a predictable and consistent menstrual cycle tracks the days that she is fertile. The typical woman has approximately 9 fertile days a month and either avoids intercourse on those days or uses an alternative birth control method for that period of time. The failure rate is between 2-23%.
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Therefore most of the activity of injected MPA probably results from the parent drug rather than the hydrolysis product. Finally many papers claim to use MP but are really using MPA (see for example PMID 1119869, "Medroxyprogesterone was provided as Depo-Provera"). Boghog 18:48, 6 July 2010 (UTC)