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Aspiration is defined as inhalation of oropharyngeal or gastric contents into the pulmonary tree. Depending on the composition of the aspirate, three complications have been described: [4] Chemical pneumonitis may develop whose severity depends on the pH value and quantity of aspirate. [4]
This is referred to as oropharyngeal dysphagia and can be a result of structural abnormalities (strictures, stenosis, mediastinal and neck masses, etc.), connective tissue diseases, neuropathy, or other central nervous system-related disorders (stroke, head injury, ALS, Guillain-Barre, etc.).
Blood-streaked sputum –an indicator of possible inflammation of the throat (larynx and/or trachea) or bronchi; lung cancer; other bleeding erosions, ulcers, or tumors of the lower airway. Pink sputum – it indicates sputum evenly mixed with blood from alveoli and/or small peripheral bronchi as is seen in potential pulmonary edema.
Phlegm is more related to disease than mucus, and can be troublesome for the individual to excrete from the body. Phlegm is a thick secretion in the airway during disease and inflammation. Phlegm usually contains mucus with virus, bacteria, other debris, and sloughed-off inflammatory cells.
"Mucus is very helpful in terms of our immune system," Elliott says. "When you have a foreign particle like pollen or a virus or bacteria, your mucosal cells — which produce mucus — are ...
Pharyngeal aspiration is often performed on mice [1] and rats. [5] Prior to introduction of the stubstance, the animal is anesthetized and its tongue extended, preventing the animal from swallowing the material and allowing it to be aspirated into the lungs over the course of at least two deep breaths.
"Normal healthy mucus travels in a pattern from the front of the nose to the throat by a special way called mucus transport (mucociliary transport), through tiny hairs pushing it along the nose ...
Accumulated mucus in the airways resulting from impaired mucociliary clearance, that may involve mucus hypersecretion. Effective mucociliary clearance depends on a number of factors including the numbers of cilia, and their structure particularly their height, and the quality of the mucus produced that needs to be maintained at a correct ...