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Bacterial secretion systems are protein complexes present on the cell membranes of bacteria for secretion of substances. Specifically, they are the cellular devices used by pathogenic bacteria to secrete their virulence factors (mainly of proteins) to invade the host cells.
A Type VIII secretion system is a type of secretion system found within the inner and outer membranes of gram-negative bacteria. This system is also referred to as the curli biogenesis pathway or the extracellular nucleation-precipitation pathway. It is associated with the formation of biofilms and infecting hosts. [1] Curli formation is ...
The bacterial type IV secretion system, also known as the type IV secretion system or the T4SS, is a secretion protein complex found in gram negative bacteria, gram positive bacteria, and archaea. It is able to transport proteins and DNA across the cell membrane. [1] The type IV secretion system is just one of many bacterial secretion systems.
The prototypic Type IVA secretion system is the VirB complex of Agrobacterium tumefaciens. [11] Protein members of this family are components of the type IV secretion system. They mediate intracellular transfer of macromolecules via a mechanism ancestrally related to that of bacterial conjugation machineries. [12] [13]
The type 2 secretion system (often referred to as the type II secretion system or by the initials T2SS) is a type of protein secretion machinery found in various species of Gram-negative bacteria, including many human pathogens such as Pseudomonas aeruginosa and Vibrio cholerae. [1]
The type VI secretion system (T6SS) is one of the bacterial secretion systems, membrane protein complexes, used by a wide range of gram-negative bacteria to transport effectors. Effectors are moved from the interior of a bacterial cell, across the membrane into an adjacent target cell.
A transmission electron microscope image of isolated T3SS needle complexes from Salmonella Typhimurium. The type III secretion system (T3SS or TTSS) is one of the bacterial secretion systems used by bacteria to secrete their effector proteins into the host's cells to promote virulence and colonisation.
Type VII secretion systems are bacterial secretion systems first observed in the phyla Actinomycetota and Bacillota. Bacteria use such systems to transport, or secrete, proteins into the environment. [1] The bacterial genus Mycobacterium uses type VII secretion systems (T7SS) to secrete proteins across their cell envelope. [2]