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DA2PP is a multivalent vaccine for dogs that protects against the viruses indicated by the alphanumeric characters forming the abbreviation: D for canine distemper, [1] A2 for canine adenovirus type 2, which offers cross-protection to canine adenovirus type 1 (the more pathogenic of the two strains) (see Canine adenovirus), [1] the first P for canine parvovirus, [1] and the second P for ...
Programs in this field have contributed both to the health of dogs and to the public health. In countries where routine rabies vaccination of dogs is practiced, for example, rabies in humans is reduced to a very rare event. Currently, there are geographically defined core vaccines and individually chosen non-core vaccine recommendations for ...
Canine distemper virus (CDV) (sometimes termed "footpad disease") is a viral disease that affects a wide variety of mammal families, [2] including domestic and wild species of dogs, coyotes, foxes, pandas, wolves, ferrets, skunks, raccoons, and felines, as well as pinnipeds, some primates, and a variety of other species.
Dogs will typically recover from kennel cough within a few weeks. However, secondary infections could lead to complications that could do more harm than the disease itself. [ 2 ] Several opportunistic invaders have been recovered from the respiratory tracts of dogs with kennel cough, including Streptococcus , Pasteurella , Pseudomonas , and ...
Starting in 1881, dried spinal cord material from infected rabbits was given to dogs to inoculate them against rabies. [10] The infected nerve tissue was dried to weaken the virus. [11] Subsequently, in 1885, the vaccine was given to a 9-year-old boy infected with the rabies disease, Joseph Meister, who survived when no one had before. [10]
A pentavalent vaccine combines five vaccines into one dose. Pentavalent vaccines include: DTwP-HepB-Hib vaccine, used by UNICEF in low/middle income countries;
Most combination vaccines for dogs contain a modified canine adenovirus type-2. [4] CAV-2 is one of the causes of respiratory infections in dogs, but it is similar enough to CAV-1 that vaccine for one creates immunity for both. CAV-2 vaccine is much less likely to cause side effects than CAV-1 vaccine. [2]
Animal models are used to learn more about a disease, its diagnosis and its treatment, with animal models predicting human toxicity in up to 71% of cases. [1] The human equivalent dose (HED) or human equivalent concentration (HEC) is the quantity of a chemical that, when administered to humans, produces an effect equal to that produced in test animals by a smaller dose. [2]
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