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Cyclopentolate is often chosen as a milder, shorter-lasting, cycloplegic alternative to atropine, another cycloplegic agent which lasts much longer. Tropicamide is an even shorter-lasting cycloplegic than cyclopentolate, but is less reliable for finding latent hyperopia. Cyclopentolate drops act rapidly to dilate the pupil. [5]
Every 8–12 hours: 15-20%: eye irritation, bitter taste Brinzolamide: Azopt: Decrease aqueous production: Every 8–12 hours: 15-20%: eye irritation, bitter taste Acetazolamide: Diamox: Decrease aqueous production: Every 6–12 hours: 15-20%: malaise, depression, weight loss, kidney stones
Cyclopentolate, Atropine, Tropicamide, and Homatropine are the typical cycloplegic eye drops used once daily to treat spasm of accommodation by relaxing the ciliary muscle. One side effect is blurred vision since these induce dilation.
Tropicamide, sold under the brand name Mydriacyl among others, is a medication used to dilate the pupil and help with examination of the eye. [3] Specifically it is used to help examine the back of the eye. [4] It is applied as eye drops. [3] Effects occur within 40 minutes and last for up to a day. [3]
All cycloplegics are also mydriatic (pupil dilating) agents and are used as such during eye examination to better visualize the retina. When cycloplegic drugs are used as a mydriatic to dilate the pupil, the pupil in the normal eye regains its function when the drugs are metabolized or carried away.
Anti-muscarinic topical medications in children under 18 years of age may slow the worsening of myopia. [105] [106] These treatments include pirenzepine gel, cyclopentolate eye drops, and atropine eye drops. While these treatments were shown to be effective in slowing the progression of myopia and reducing eyeball elongation associated with the ...
[5] [12] To keep the specific drug in the therapeutic window using eye drops the topical must be applied approximately every 30 minutes in order to be fully effective. [ 5 ] [ 12 ] Having to apply eye drops every 30 minutes would be nearly impossible for anyone and is not the ideal mechanism by which to deliver such drugs to the eye.
Mydriasis is the dilation of the pupil, usually having a non-physiological cause, [3] or sometimes a physiological pupillary response. [4] Non-physiological causes of mydriasis include disease, trauma, or the use of certain types of drugs.