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Cerebrospinal fluid (CSF) is a clear, colorless transcellular body fluid found within the meningeal tissue that surrounds the vertebrate brain and spinal cord, and in the ventricles of the brain. CSF is mostly produced by specialized ependymal cells in the choroid plexuses of the ventricles of the brain, and absorbed in the arachnoid ...
The blood–cerebrospinal fluid barrier (BCSFB) is a fluid–brain barrier that is composed of a pair of membranes that separate blood from CSF at the capillary level and CSF from brain tissue. [14] The blood–CSF boundary at the choroid plexus is a membrane composed of epithelial cells and tight junctions that link them. [ 14 ]
Within the ventricles of the brain, a population of modified ependymal cells and capillaries together known as the tela choroidea form a structure called the choroid plexus, which produces the CSF. [5] Modified tight junctions between epithelial cells control fluid release. This release allows free exchange between CSF and nervous tissue of ...
The ventricles are filled with cerebrospinal fluid (CSF) which bathes and cushions the brain and spinal cord within their bony confines. CSF is produced by modified ependymal cells of the choroid plexus found in all components of the ventricular system except for the cerebral aqueduct and the posterior and anterior horns of the lateral ventricles.
The ependyma and vascular pia mater – the tela choroidea, form regions of minute projections known as a choroid plexus that projects into each ventricle. [ 1 ] [ 2 ] The choroid plexus produces most of the cerebrospinal fluid of the central nervous system that circulates through the ventricles of the brain, the central canal of the spinal ...
According to this model, cerebrospinal fluid (CSF), an ultrafiltrated plasma fluid secreted by choroid plexuses in the cerebral ventricles, flows into the paravascular space around cerebral arteries, contacts and mixes with interstitial fluid (ISF) and solutes within the brain parenchyma, and exits via the cerebral venous paravascular spaces ...
Tanycytes are highly specialized ependymal cells found in the third ventricle of the brain, and on the floor of the fourth ventricle. Each tanycyte has a long basal process that extends deep into the hypothalamus. It is possible that their function is to transfer chemical signals from the cerebrospinal fluid to the central nervous system.
More specifically, the median eminence allows for the transport of neurohormones between the CSF and the peripheral blood supply. [36] The major cell type that makes up the median eminence are specialized ependymal cells known as tanycytes. These contribute to the organ's ability to selectively allow macromolecules to pass from the central to ...