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blast.ncbi.nlm.nih.gov /Blast.cgi In bioinformatics , BLAST ( basic local alignment search tool ) [ 3 ] is an algorithm and program for comparing primary biological sequence information, such as the amino-acid sequences of proteins or the nucleotides of DNA and/or RNA sequences.
HTML is the default output format for NCBI's web-page. Results for NCBI-BLAST are presented in graphical format with all the hits found, a table with sequence identifiers for the hits having scoring related data, along with the alignments for the sequence of interest and the hits received with analogous BLAST scores for these. [8]
[4] [5] NCBI is the home of GenBank, [6] the U.S. node of the International Sequence Database Consortium, and PubMed, one of the most heavily used sites in the world for the search and retrieval of biomedical information. Lipman is one of the original authors of the BLAST sequence alignment program, and a respected figure in bioinformatics.
HPC-BLAST: NCBI compliant multinode and multicore BLAST wrapper. Distributed with the latest version of BLAST, this wrapper facilitates parallelization of the algorithm on modern hybrid architectures with many nodes and many cores within each node. [2] Protein: Burdyshaw CE, Sawyer S, Horton MD, Brook RG, Rekapalli B: 2017 CS-BLAST
Gish developed the first BLAST API, which was used in EST [10] annotation and Entrez data production, as well as in the NCBI BLAST version 1.4 application suite (Gish, unpublished). Gish was also the creator of and project manager for the earliest NCBI Dispatcher for distributed services (inspired by CORBA's Object Request Broker).
The database search by BLAST requires input data to be in a correct format (e.g. FASTA, GenBank, PIR or EMBL format). Users may also designate the specific databases to be searched, select scoring matrices to be used and other parameters prior to the tool run.
The NCBI team also collaborates with expert groups to develop the database and its annotation on a regular basis. Continuous evaluation of review papers and new reports of resistance proteins augment these sources. [2] While some AMR gene identification tools rely on BLAST-based methodologies, others employ hidden Markov model (HMM) approaches ...
Eugene Wimberly "Gene" Myers, Jr. (born December 31, 1953) is an American computer scientist and bioinformatician, who is best known for contributing to the early development of the NCBI's BLAST tool for sequence analysis.