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11657 Ensembl ENSG00000163631 ENSMUSG00000029368 UniProt P02768 P07724 RefSeq (mRNA) NM_000477 NM_009654 RefSeq (protein) NP_000468 NP_033784 Location (UCSC) Chr 4: 73.4 – 73.42 Mb Chr 5: 90.61 – 90.62 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Human serum albumin is the serum albumin found in human blood. It is the most abundant protein in human blood plasma ; it ...
Albumin is an acute negative phase respondent and not a reliable indicator of nutrition status. [10] Low albumin levels can also indicate chronic malnutrition from protein losing enteropathy. [3] This is often caused or exacerbated by ulcerative colitis, [11] but can also be seen in cardiac disease and systemic lupus erythematosus. [3]
Under normal conditions a 24-hour urine sample should not exceed 80 milligrams or 10 milligrams per decilitre. [11] Hypoalbuminemia of less than 2.5 g/dL, [9] that exceeds the liver clearance level, that is, protein synthesis in the liver is insufficient to increase the low blood protein levels. Edema is thought to be caused by two mechanisms.
A decreased level of albumin, however, is common in many diseases, including liver disease, malnutrition, malabsorption, protein-losing nephropathy and enteropathy. [ 9 ] Albumin – alpha-1 interzone
Diagnosis is based on the measurement of abnormal levels of urinary albumin in an individual with diabetes [27] coupled with exclusion of other causes of albuminuria. Albumin measurements are defined as follows: [28] Normal albuminuria: urinary albumin excretion <30 mg/24h; Microalbuminuria: urinary albumin excretion in the range of 30–299 mg ...
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More specifically, optimal levels are generally close to a central tendency of the values found in the population. However, usual and optimal levels may differ substantially, most notably among vitamins and blood lipids, so these tables give limits on both standard and optimal (or target) ranges.
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