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Three main changes are seen in the mechanism of Raynaud's phenomenon which are reduced blood flow, blood vessel constriction, and neurogenic, inflammatory, and immune responses. It is induced by mental stress and a cold atmosphere. In all cases, the primary cause is an underlying hyperactivation of the sympathetic nervous system. [19]
Illustration of how the buildup of lipids cause a blockage of blood flow to the portion of the artery below the narrowing. Peripheral arterial disease is considered to be a set of chronic or acute syndromes, generally derived from the presence of occlusive arterial disease, which causes inadequate blood flow to the limbs. [51] [52]
Erythromelalgia in left hand: Specialty: Oncology: Causes: There was a study done in 2013 where two Vietnamese patients were diagnosed with primary erythromelalgia. Patient A was a 33-year old female diagnosed with primary erythromelalgia at age 30 and suffered from burning and pain in her feet since she was 8 years old (Wu et. al 2013).
Gangrene toes in a diabetic. Gangrene is a type of tissue death caused by a lack of blood supply. [4] The feet and hands are most commonly affected. [1] If the gangrene is caused by an infectious agent, it may present with a fever or sepsis.
The most common cause of compartment syndrome in children is traumatic injury. [77] In children <10 years of age, the cause is usually vascular injury or infection. [78] In children >14 years of age, the cause is usually due to trauma or surgical positioning. [78] Treatment for compartment syndrome in children is the same as adults. [72]
Discoloration of the hands, one hand colder than the other hand, weakness of the hand and arm muscles, and tingling are commonly present. [citation needed] Only 1% of people with carpal tunnel syndrome have concomitant TOS. [7] Repetitive motions can cause enlargement of muscles which causes compression of veins.
De Sénac concluded from an autopsy that cyanosis was caused by a heart defect that led to the mixture of arterial and venous blood circulation. But it was not until 1919, when Dr. Lundsgaard was able to derive the concentration of deoxyhemoglobin (8 volumes per cent) that could cause cyanosis. [13]
There is a recurrent acute and chronic inflammation and thrombosis of arteries and veins of the hands and feet. The main symptom is pain in the affected areas, at rest and while walking (claudication). [1] The impaired circulation increases sensitivity to cold. Peripheral pulses are diminished or absent. There are color changes in the extremities.
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