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Travelers' diarrhea (TD) is a stomach and intestinal infection. TD is defined as the passage of unformed stool (one or more by some definitions, three or more by others) while traveling. [ 2 ] [ 3 ] It may be accompanied by abdominal cramps, nausea, fever, headache and bloating. [ 3 ]
Azithromycin, sold under the brand names Zithromax (in oral form) and Azasite (as an eye drop), is an antibiotic medication used for the treatment of several bacterial infections. [10] This includes middle ear infections , strep throat , pneumonia , traveler's diarrhea , and certain other intestinal infections . [ 10 ]
Alternatively, a single dose azithromycin or levofloxacin may be prescribed. [33] If diarrhea persists despite therapy, travelers should be evaluated and treated for possible parasitic infection. [citation needed] Cryptosporidium can be quite dangerous to patients with compromised immune systems.
Enteroaggregative Escherichia coli (EAEC or EAggEC) are a pathotype of Escherichia coli which cause acute and chronic diarrhea in both the developed and developing world. [1] [2] They may also cause urinary tract infections. [2] EAEC are defined by their "stacked-brick" pattern of adhesion to the human laryngeal epithelial cell line HEp-2. [3]
Rifaximin, is a non-absorbable, broad spectrum antibiotic mainly used to treat travelers' diarrhea.It is based on the rifamycin antibiotics family. Since its approval in Italy in 1987, it has been licensed in over more than 30 countries for the treatment of a variety of gastrointestinal diseases like irritable bowel syndrome, and hepatic encephalopathy.
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It is a common cause of diarrhea in those who are hospitalized and is frequently associated with antibiotic use. [32] Staphylococcus aureus infectious diarrhea may also occur in those who have used antibiotics. [33] Acute "traveler's diarrhea" is usually a type of bacterial gastroenteritis, while the persistent form is usually parasitic. [34]
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