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The Papanicolaou test (abbreviated as Pap test, also known as Pap smear (AE), [1] cervical smear (BE), cervical screening (BE), [2] or smear test (BE)) is a method of cervical screening used to detect potentially precancerous and cancerous processes in the cervix (opening of the uterus or womb) or, more rarely, anus (in both men and women). [3]
Georgios Nikolaou Papanikolaou (or George Papanicolaou / ˌ p æ p ə ˈ n ɪ k ə l aʊ /; Greek: Γεώργιος Ν. Παπανικολάου [papanikoˈlau]; 13 May 1883 – 19 February 1962) was a Greek physician, zoologist and microscopist who was a pioneer in cytopathology and early cancer detection, and inventor of the pap smear for detection of cervical cancer.
Cell nuclei stained blue. Papanicolaou stain (also Papanicolaou's stain and Pap stain) is a multichromatic (multicolored) cytological staining technique developed by George Papanicolaou in 1942. [1][2][3] The Papanicolaou stain is one of the most widely used stains in cytology, [1] where it is used to aid pathologists in making a diagnosis.
Andromachi Papanikolaou. Andromachi " Mary " Mavrogeni Papanikolaou[note 1] (1890-13 October 1982) was a Greek laboratory technician and the wife of Georgios Papanikolaou, the Greek pathologist who independently invented the pap test. For 21 years, Mary Papanikolaou volunteered to have her cervix sampled and smeared by her husband to help with ...
The Bethesda system (TBS), officially called The Bethesda System for Reporting Cervical Cytology, is a system for reporting cervical or vaginal cytologic diagnoses, [1] used for reporting Pap smear results. It was introduced in 1988 [2] and revised in 1991, [3] 2001, [1][4][5] and 2014. [6] The name comes from the location (Bethesda, Maryland ...
A pelvic examination is the physical examination of the external and internal female pelvic organs. [1] It is frequently used in gynecology for the evaluation of symptoms affecting the female reproductive and urinary tract, such as pain, bleeding, discharge, urinary incontinence, or trauma (e.g. sexual assault). [2][3] It can also be used to ...
Cervical cancer screening is a medical screening test designed to identify risk of cervical cancer. Cervical screening may involve looking for viral DNA, and/or to identify abnormal, potentially precancerous cells within the cervix as well as cells that have progressed to early stages of cervical cancer. [1][2] One goal of cervical screening is ...
The Pap smear was developed by Georgios Papanikolaou in 1928. [49] A LEEP procedure using a heated loop of platinum to excise a patch of cervical tissue was developed by Aurel Babes in 1927. [50] In some parts of the developed world including the UK, the Pap test has been superseded with liquid-based cytology. [51]