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Pralidoxime (2-pyridine aldoxime methyl chloride) or 2-PAM, usually as the chloride or iodide salts, belongs to a family of compounds called oximes that bind to organophosphate-inactivated acetylcholinesterase. [1] It is used to treat organophosphate poisoning [2] in conjunction with atropine and either diazepam or midazolam. It is a white solid.
Pyridine-3-carbaldehyde, also known as nicotinaldehyde, is an organic compound with the formula C 5 H 4 NCHO. It is one of three isomeric pyridinaldehydes. The other isomers are pyridine-2-carboxaldehyde and pyridine-4-carboxaldehyde. It is a colorless liquid that is routinely available commercially. It can be produced from nicotinonitrile ...
98-98-6 59-67-6 55-22-1 All isomers share the molecular weight 123,11 g/mol and the chemical formula C 6 H 5 NO 2. See also. Pyridinedicarboxylic acid
Pyridine-2-carbaldehyde, also called 2-formylpyridine, is an organic compound with the formula NC 5 H 4 CHO. It is one of three isomeric pyridinaldehydes. The other isomers are pyridine-3-carboxaldehyde and pyridine-4-carboxaldehyde. Pyridine-2-carbaldehyde is a colorless oily liquid with a distinctive odor.
In 1989, 26,000 tonnes of pyridine was produced worldwide. Other major derivatives are 2-, 3-, 4-methylpyridines and 5-ethyl-2-methylpyridine. The combined scale of these alkylpyridines matches that of pyridine itself. [2] Among the largest 25 production sites for pyridine, eleven are located in Europe (as of 1999). [24]
Nicotinonitrile or 3-cyanopyridine is an organic compound with the formula NCC 5 H 4 N. The molecule consists of a pyridine ring with a nitrile group attached to the 3-position. A colorless solid, it is produced by ammoxidation of 3-methylpyridine: [2] H 3 CC 5 H 4 N + NH 3 + 1.5 O 2 → NCC 5 H 4 N + 3 H 2 O. Nicotinonitrile is a precursor to ...
Saruparib is a investigational new drug that is being evaluated for the treatment of cancer. [1] It first-in-class selective inhibitor of poly-ADP ribose polymerase 1 (PARP1), designed to treat cancers with homologous recombination repair (HRR) deficiencies as a result of mutations in BRCA1 , BRCA2 , PALB2 , RAD51C , or RAD51D genes.
2-Picoline was the first pyridine compound reported to be isolated in pure form. It was isolated from coal tar in 1846 by T. Anderson. [2] This chemistry was practiced by Reilly Industries. [3] It is now mainly produced by two principal routes. One method involves the condensation of acetaldehyde and ammonia in the presence of an oxide catalyst ...
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