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A mycotoxin (from the Greek μύκης mykes, "fungus" and τοξικός toxikos, "poisonous") [1] [2] is a toxic secondary metabolite produced by fungi [3] [4] and is capable of causing disease and death in both humans and other animals.
Mycotoxicology is the branch of mycology that focuses on analyzing and studying the toxins produced by fungi, known as mycotoxins. [1] In the food industry it is important to adopt measures that keep mycotoxin levels as low as practicable, especially those that are heat-stable.
Listeriolysin O toxin is an exotoxin produced by Listeria monocytogenes and is associated with foodborne systemic illness and meningitis. [7] Listeriolysin O toxin is classified as a pore-forming toxin that targets host cholesterol cells, inserting a pore into the host cell plasma membrane and permanently disabling cellular functioning. [3]
The toxins, named mycotoxins, deter other organisms from consuming the food the fungi colonise. As with bacterial toxins, there is a wide array of fungal toxins. Arguably one of the more dangerous mycotoxins is aflatoxin produced by certain species of the genus Aspergillus (notably A. flavus). If ingested repeatedly, this toxin can cause ...
The trichothecene mycotoxins are toxic to humans, other mammals, birds, fish, a variety of invertebrates, plants, and eukaryotic cells. [21] The specific toxicity varies depending on the particular toxin and animal species, however the route of administration plays a significantly higher role in determining lethality.
Citrinin is a mycotoxin which is often found in food. It is a secondary metabolite produced by fungi that contaminates long-stored food and it can cause a variety of toxic effects, including kidney, liver and cell damage. Citrinin is mainly found in stored grains, but sometimes also in fruits and other plant products.
A toxin is a naturally occurring poison [1] produced by metabolic activities of living cells or organisms. [2] They occur especially as proteins , often conjugated . [ 3 ] The term was first used by organic chemist Ludwig Brieger (1849–1919), [ 4 ] derived from toxic .
Gliotoxin is a sulfur-containing mycotoxin that belongs to a class of naturally occurring 2,5-diketopiperazines [1] produced by several species of fungi, especially those of marine origin. It is the most prominent member of the epipolythiopiperazines, a large class of natural products featuring a diketopiperazine with di- or polysulfide linkage.