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Cyclopentolate is often chosen as a milder, shorter-lasting, cycloplegic alternative to atropine, another cycloplegic agent which lasts much longer. Tropicamide is an even shorter-lasting cycloplegic than cyclopentolate, but is less reliable for finding latent hyperopia. Cyclopentolate drops act rapidly to dilate the pupil. [5]
It is applied as eye drops. [3] Effects occur within 40 minutes and last for up to a day. [3] Common side effects include blurry vision, increased intraocular pressure, and sensitivity to light. [3] Another rare but severe side effect is psychosis, particularly in children. [3] It is unclear if use during pregnancy is safe for the fetus. [5]
Spasm of accommodation is frequently resistant to treatment. However, some patients do find relief through the use of daily eye dilation with cycloplegic drops. One side effect of cycloplegic drops is that they often have BAK as a preservative ingredient, which, with daily use, can erode the tear shield:
Topical atropine is used as a cycloplegic, to temporarily paralyze the accommodation reflex, and as a mydriatic, to dilate the pupils. [15] Atropine degrades slowly, typically wearing off in 7 to 14 days, so it is generally used as a therapeutic mydriatic, whereas tropicamide (a shorter-acting cholinergic antagonist) or phenylephrine (an α-adrenergic agonist) is preferred as an aid to ...
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[1] [6] [7] However, due to its side effects, it is no longer typically used for long-term management. [8] Onset of effects with the drops is typically within an hour and lasts for up to a day. [1] By mouth it is used for dry mouth as a result of Sjögren syndrome or radiation therapy. [9]
Atropa bella-donna has a long history of use as a medicine, cosmetic, and poison. [14] [4] [15] Known originally under various folk names (such as "deadly nightshade" in English), the plant was named Atropa bella-donna by Carl Linnaeus (1707–1778) when he devised his classification system.
She advises anyone who menstruates to tell their doctor if their cycles are longer than 35 days or shorter than 21 days, they bleed for more than seven days, they soak through one or more tampons ...