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  2. Stem cell transplantation for articular cartilage repair

    en.wikipedia.org/wiki/Stem_cell_transplantation...

    Marrow-nucleated cells are used every day in regenerative orthopedics. The knee microfracture surgery technique relies on the release of these cells into a cartilage lesion to initiate fibrocartilage repair in osteochondral defects. [13] In addition, this cell population has also been shown to assist in the repair of non-union fractures. [14]

  3. Knee cartilage replacement therapy - Wikipedia

    en.wikipedia.org/wiki/Knee_cartilage_replacement...

    There are several different repair options available for cartilage damage or failure. "Maci" or autologous cultured chondrocytes on porcine collagen membrane, is a treatment to correct cartilage defects in the knee. This treatment has been approved by the Food and Drug Administration in 2016 for adult treatment only. [1]

  4. Spheroids of human autologous matrix-associated chondrocytes

    en.wikipedia.org/wiki/Spheroids_of_human...

    Spheroids of human autologous matrix-associated chondrocytes, sold under the brand name Spherox, is a medication used to repair defects to the cartilage in the knee in adults who are experiencing knee pain and problems moving the knee. [1] It is used where the affected area is no larger than 10 cm 2 (1.6 sq in). [1]

  5. Autologous chondrocyte implantation - Wikipedia

    en.wikipedia.org/wiki/Autologous_Chondrocyte...

    Techniques such as the EELS-TALC [4] to enhance ACI and its next generation advancement called Matrix Assisted Chondrocyte Implantation (MACI) [5] with enabling chondrocytes to be tissue engineered with long term native knee cartilage phenotype maintenance in vitro and in vivo, [6] [7] with the engineered tissue construct containing stem cell progenitors [8] along with those expressing ...

  6. Stem-cell therapy - Wikipedia

    en.wikipedia.org/wiki/Stem-cell_therapy

    Stem-cell therapy uses stem cells to treat or prevent a disease or condition. [1] As of 2024, the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation. [2] [3] This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from umbilical cord blood.

  7. Articular cartilage stem cell paste grafting - Wikipedia

    en.wikipedia.org/wiki/Articular_cartilage_stem...

    Articular cartilage stem cell paste grafting was initially described by Kevin R. Stone M.D., a San Francisco-based orthopedic surgeon, in 1997 . The technique was devised in response to reports that many of the contemporary cartilage restoration procedures lead to the development of fibrocartilage, not true hyaline articular cartilage. Knowing ...

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