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Phenacyl bromide is the organic compound with the formula C 6 H 5 C(O)CH 2 Br. This colourless solid is a powerful lachrymator as well as a useful precursor to other organic compounds. It is prepared by bromination of acetophenone: [2] C 6 H 5 C(O)CH 3 + Br 2 → C 6 H 5 C(O)CH 2 Br + HBr. The compound was first reported in 1871. [3]
The combination was first introduced as the name Trigesic, as the formula of 125 mg paracetamol, 230 mg aspirin, and 30 mg caffeine, in July 1950 by Squibb, which is now Bristol Myers Squibb, but was recalled in the following year due to several reports that the drug might cause blood dyscrasia. [5]
Another example is Bex, a once popular Australian compound analgesic which is no longer sold. It contained 42% aspirin, 42% phenacetin, plus caffeine. [2]The United States Food and Drug Administration also now requires that manufacturers of compound analgesics unequivocally state each ingredient's purpose.
It came in the form of APC (aspirin–phenacetin–caffeine) tablets or powder, containing 42% aspirin and 42% phenacetin plus caffeine. [1] Beckers Ltd - outside view of Bex building. Bex was a product of Beckers Pty Ltd, originally based at Pym Street, Dudley Park, South Australia, [2] but which relocated to Sydney in the 1960s. [3]
In organic chemistry, a phenacyl group is an aromatic substituent that consists of a phenyl group attached to an acyl group. A molecule containing a phenacyl group has the formula RCH 2 (CO)C 6 H 5 and the structure shown to the right. Here, R denotes the remainder of the molecule; for instance, if R is Br, then the compound could be called ...
Tear gas in use in France 2007 Exploded tear gas canister in the air in Greece. Tear gas, also known as a lachrymatory agent or lachrymator (from Latin lacrima 'tear'), sometimes colloquially known as "mace" after the early commercial self-defense spray, is a chemical weapon that stimulates the nerves of the lacrimal gland in the eye to produce tears.
Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedy PainAid. It was also an ingredient in the over-the-counter pain remedy BC Powder but was removed from the formulation in 2009, and Excedrin used the ingredient from 1960 to 1980 in conjunction with aspirin , acetaminophen , and caffeine .
4-686-293-01, also known as Agent 1-10, is a highly potent experimental carbamate nerve agent, patented in May 1967 by the US army. [1] Due to its high molecular weight and thermal stability, it can remain embedded within various surfaces and clothes for prolonged periods of time.