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Skeletal formula of the antibiotic linezolid, highlighting the oxazolidinone pharmacophore (in blue) and desirable structural characteristics (in orange). Created using ACD/ChemSketch 10.0 and Inkscape. Date: 24 June 2009: Source: Own work based on: Brickner SJ (1996).
The 23S ribosomal RNA is composed of six domains forming a complex network of molecular interactions. A central single-stranded region connects all of the domains through base-pairing of the two halves, forming Helix 26a.
Linezolid is a member of the oxazolidinone class of medications. [10] Linezolid was discovered in the mid-1990s, and was approved for commercial use in 2000. [16] [17] It is on the World Health Organization's List of Essential Medicines. [18] The World Health Organization classifies linezolid as critically important for human medicine. [19]
The following other wikis use this file: Usage on ar.wikipedia.org لينيزوليد; Usage on azb.wikipedia.org لینزولید; Usage on cy.wikipedia.org
English: Translation: Illustrates how a ribosome a mRNA and lots of tRNA molecules work together to produce peptides or proteins. Français : Diagramme montrant comment la traduction de l'ARN messager et la synthèse protéique se font dans les ribosomes.
Simplified schematic of mRNA translation. A protein synthesis inhibitor is a compound that stops or slows the growth or proliferation of cells by disrupting the processes that lead directly to the generation of new proteins. [1] A ribosome is a biological machine that utilizes protein dynamics on nanoscales to translate RNA into proteins
Five prime cap - mRNA Processing five prime untranslated region - region of a messenger RNA coding region - portion of a gene's DNA or RNA, composed of exons, that codes for protein; composed of codons, which are decoded, translated into proteins by the ribosome; begins with the start codon and end with a stop codon
Eukaryotic mRNA precursors must be processed in the nucleus (e.g., capping, polyadenylation, splicing) in ribosomes before they are exported to the cytoplasm for translation. Translation can also be affected by ribosomal pausing, which can trigger endonucleolytic attack of the tRNA, a process termed mRNA no-go decay. Ribosomal pausing also aids ...