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Alpha-gal syndrome (AGS), also known as alpha-gal allergy or mammalian meat allergy (MMA), [1] is a type of acquired allergy characterized by a delayed onset of symptoms (3–8 hours) after ingesting mammalian meat. The condition results from past exposure to certain tick bites and was first reported in 2002.
The range of symptoms is vast; alpha-gal syndrome can cause hives, heartburn, nausea or vomiting, diarrhea, drops in blood pressure, dizziness, severe stomach pain, and even anaphylaxis.
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What is alpha-gal syndrome? The lone star tick can cause an allergic reaction known as alpha-gal syndrome. The tick's saliva contains a sugar molecule called galactose-alpha-1,3-galactose (alpha-gal).
L-α-Glycerophosphorylcholine (alpha-GPC, choline alfoscerate, sn-glycero-3-phosphocholine) is a natural choline compound found in the brain. It is also a parasympathomimetic acetylcholine precursor [ 1 ] which has been investigated for its potential for the treatment of Alzheimer's disease [ 2 ] and other dementias .
Neuroinflammation is widely regarded as chronic, as opposed to acute, inflammation of the central nervous system. [5] Acute inflammation usually follows injury to the central nervous system immediately, and is characterized by inflammatory molecules, endothelial cell activation, platelet deposition, and tissue edema. [6]
Galactose-α-1,3-galactose, commonly known as alpha gal and the Galili antigen, is a carbohydrate found in most mammalian cell membranes. It is not found in catarrhines , [ 1 ] including humans, who have lost the GGTA1 gene.
To understand Alpha-gal syndrome, you first must understand what Alpha-gal is. According to the Centers for Disease Control and Prevention, alpha-gal is a sugar molecule found in most mammals, but ...