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Treatment. The main treatment for severe hemophilia involves replacing the clotting factor you need through a tube in a vein. This replacement therapy can be given to treat a bleeding episode in progress. It can also be given on a regular schedule at home to help prevent bleeding episodes.
Internal bleeding can damage your organs and tissues and be life-threatening. Hemophilia is almost always a genetic disorder. Treatment includes regular replacement of the specific clotting factor that is reduced. Newer therapies that don't contain clotting factors also are being used.
Advanced diagnosis and treatment. Hemophilia is rare, so it's vital to get an accurate diagnosis and treatment. Mayo Clinic has been designated a comprehensive hemophilia center by the Centers for Disease Control and Prevention.
Mayo Clinic researchers are examining the effectiveness of a variety of precautions taken to reduce the risk of hemophiliac hemorrhage during surgeries. Mayo scientists are also studying the molecular genetics of hemophilia. This promising field of study may lead to gene therapy in the future.
The U.S. Food and Drug Administration (FDA) has approved gene therapy products for several conditions, including cancer, spinal muscular atrophy, hemophilia and sickle cell disease. But for most people, gene therapy is available only as part of a clinical trial.
Many doctors consider desmopressin (DDAVP) the first treatment for managing von Willebrand disease. It can be used before minor surgical procedures to help control bleeding. You might be given a trial of desmopressin to make sure it's effective for you.
Management of sickle cell anemia is usually aimed at avoiding pain episodes, relieving symptoms and preventing complications. Treatments might include medicines and blood transfusions. For some children and teenagers, a stem cell transplant might cure the disease.
Mayo Clinic Rochester's Hemophilia Treatment Center (HTC) provides specialty care to patients with a bleeding disorder. The center provides whole-patient care, including: Diagnosis; Disease and symptom management; Coordinated care with other Mayo Clinic specialties (if needed) On-site coagulation lab All tests can be done on site with quick results
Treatment might include oxygen, pain relievers, and hydration with fluids given through a vein, called intravenous, to reduce pain and prevent complications. Receiving blood, called a transfusion, and taking folic acid supplements and antibiotics might be involved.
For treatment of hemophilia A or won Willebrand disease: Adults and children 13 years of age and older—One spray (0.1 milliliter) in each nostril as a single dose per day. Your doctor may adjust the dose as needed. Children 11 months to 12 years of age—Use and dose must be determined by your doctor.