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Haemophilia B, also spelled hemophilia B, is a blood clotting disorder causing easy bruising and bleeding due to an inherited mutation of the gene for factor IX, and resulting in a deficiency of factor IX. It is less common than factor VIII deficiency (haemophilia A). [3] Haemophilia B was first recognized as a distinct disease entity in 1952. [4]
Anemia may lead to fatigue, pale skin, severe bruising, and a fast heart rate. [9] Low platelets are associated with an increased risk of bleeding, bruising, and petechiae, with lower blood counts that impact the ability of the blood to clot. Low white blood cells increase the risk of infections. [9]
Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. [1] Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain. [1]
Various types of hemophilia and von Willebrand disease are the major genetic disorders associated with coagulopathy. Rare examples are Bernard–Soulier syndrome, Wiskott–Aldrich syndrome and Glanzmann's thrombasthenia. Gene therapy treatments may be a solution as they involve in the insertion of normal genes to replace defective genes ...
Unexplained bruising may be a warning sign of child abuse, domestic abuse, or serious medical problems such as leukemia or meningoccocal infection. Unexplained bruising can also indicate internal bleeding or certain types of cancer. Long-term glucocorticoid therapy can cause easy bruising.
Symptoms may include feeling tired, shortness of breath, easy bruising and bleeding, and increased risk of infection. [1] Occasionally, spread may occur to the brain , skin , or gums . [ 1 ] As an acute leukemia , AML progresses rapidly, and is typically fatal within weeks or months if left untreated.
Amanda explains what Wesley was doing in the caption, "In the scene, the actor is to check a notification on his phone. Each time the actor tried to look at his phone, Wesley thought he was taking ...
Some medical treatments are associated with amyloid disease, but this is rare. [19] Amyloid-forming proteins aggregate into distinctive fibrillar forms with a beta-sheet structure. [19] [20] The beta-sheet form of amyloid is proteolysis-resistant, meaning it can not be degraded or broken down. [5]