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Carcinoma is a malignancy that develops from epithelial cells. [1] Specifically, a carcinoma is a cancer that begins in a tissue that lines the inner or outer surfaces of the body, and that arises from cells originating in the endodermal, mesodermal [2] or ectodermal germ layer during embryogenesis.
of or pertaining to the veins, venous blood, and the vascular system: Latin vēna, blood-vessel, vein venule, venospasm: ventr(o)-of or pertaining to the belly, the stomach cavities Latin venter, belly, stomach, womb ventrodorsal: ventricul(o)-of or pertaining to the ventricles; any hollow region inside an organ
Accumulation of these cancer cells causes a microscopic focus of abnormal cells that are, at least initially, locally confined within the specific tissue in which the progenitor cell resided. This condition is called squamous-cell carcinoma in situ , and it is diagnosed when the tumor has not yet penetrated the basement membrane or other ...
[4] [5] The term "pre-cancer" has also been used. These abnormal cells grow in their normal place, thus in situ ( Latin for 'in its place'). For example, carcinoma in situ of the skin, also called Bowen's disease , is the accumulation of dysplastic epidermal cells within the epidermis only, that has failed to penetrate into the deeper dermis.
This way the radiation source can be applied to complex locations and minimize radiation to healthy tissue. [57] After removal of the cancer, closure of the skin for patients with a decreased amount of skin laxity involves a split-thickness skin graft. A donor site is chosen and enough skin is removed so that the donor site can heal on its own.
One accepted source is frequent, long-term application of hot objects to the body. It is possible that repeated burns on the same part of the body, such as those produced by kanger and kairo heaters (charcoal hand warmers), may produce skin cancer, especially if carcinogenic chemicals are also present. [89]
The term "field cancerization" was first used in 1953 to describe an area or "field" of epithelium that has been preconditioned by (at that time) largely unknown processes so as to predispose it towards development of cancer. [42] Since then, the terms "field cancerization" and "field defect" have been used to describe pre-malignant tissue in ...
Skin cancer is the most commonly diagnosed form of cancer in humans. [11] [12] [13] There are three main types of skin cancers: basal-cell skin cancer (BCC), squamous-cell skin cancer (SCC) and melanoma. [1] The first two, along with a number of less common skin cancers, are known as nonmelanoma skin cancer (NMSC).