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Sometimes these species are referred to as "gold salts". "Chrysotherapy" and "aurotherapy" are the applications of gold compounds to medicine. [1] Research on the medicinal effects of gold began in 1935, [2] primarily to reduce inflammation and to slow disease progression in patients with rheumatoid arthritis. The use of gold compounds has ...
Sodium aurothiomalate (INN, known in the United States as gold sodium thiomalate) is a gold compound that is used for its immunosuppressive anti-rheumatic effects. [ 2 ] [ 3 ] Along with an orally-administered gold salt, auranofin , it is one of only two gold compounds currently employed in modern medicine.
Metals in medicine are used in organic systems for diagnostic and treatment purposes. [1] Inorganic elements are also essential for organic life as cofactors in enzymes called metalloproteins . When metals are under or over-abundant in the body, equilibrium must be returned to its natural state via interventional and natural methods.
Template:Gold compounds This page was last edited on 4 January 2024, at 11:49 (UTC). Text is available under the Creative Commons Attribution-ShareAlike 4.0 License ...
Auranofin is used to treat rheumatoid arthritis.It improves arthritis symptoms including painful or tender and swollen joints and morning stiffness. [5] Auranofin is a safer treatment compared to the more common injectable gold thiolates (gold sodium thiomalate and gold thioglucose), but meta-analysis of 66 clinical trials concluded that it is somewhat less effective.
Gold thioglucose features gold in the oxidation state of +I, like other gold thiolates. It is a water-soluble, non-ionic species that is assumed to exist as a polymer. [ 1 ] Under physiological conditions, an oxidation-reduction reaction leads to the formation of metallic gold and sulfinic acid derivative of thioglucose.
Surface area plays a very important role in drug delivery and per mg of gold, as diameters decrease, the surface areas needed to transport drugs increase to the point where a single 1mL volume of 1.8 nm spherical gold nanoparticles have the same surface area as a cell phone.
Sodium aurothiosulfate, or sanocrysin, is the inorganic compound with the formula Na 3 [Au(S 2 O 3) 2]·2H 2 O. It is the trisodium salt of the coordination complex of gold(I), [Au(S 2 O 3) 2] 3−. The dihydrate, which is colorless, crystallizes with two waters of crystallization. The compound has some medicinal properties as well as potential ...