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"The non-hormonal aspect of this product is really exciting," Dr. Kelly Culwell, chief medical officer at Evofem, told TODAY. ... however, keeps vaginal pH in a normal range, between 3.5 and 4.5 ...
[16] [17] Estrogen helps maintain a thick, glycogen-rich vaginal lining, which healthy bacteria use to produce lactic acid to keep the vaginal environment acidic, reducing infection risks. [16] In premenopausal women, the main form of estrogen is called estradiol and fluctuates between 40 and 200 pg/mL, rising to 600 pg/mL during ovulation. [ 16 ]
Administering a vaginal tablet without an applicator. Intravaginal administration is a route of administration where the substance is applied inside the vagina . Pharmacologically , it has the potential advantage to result in effects primarily in the vagina or nearby structures (such as the vaginal portion of cervix ) with limited systemic ...
Vaginal estrogen, which includes creams, pills, rings, and inserts, is more commonly prescribed due to its lower risk. DHEA (prasterone) is a promising alternative that enhances vaginal health with minimal side effects and does not significantly alter hormone levels. [8]
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Because of their systemic nature, hormonal methods have the largest number of possible side effects. [14] Combined hormonal contraceptives contain estrogen and progestin hormones. [15] They can come in formulations such as pills, vaginal rings, and transdermal patches. [15]
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