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Dulaglutide, sold under the brand name Trulicity among others, [8] is a medication used for the treatment of type 2 diabetes in combination with diet and exercise. [9] [10] It is also approved in the United States for the reduction of major adverse cardiovascular events in adults with type 2 diabetes who have established cardiovascular disease or multiple cardiovascular risk factors.
A large study of more than 2 million people evaluated GLP-1 agonists' benefits and risks. The study showed that GLP-1 agonists reduced risk of substance use and psychotic disorders, seizures, neurocognitive disorders (including Alzheimer’s disease and dementia), coagulation disorders, cardiometabolic disorders, infectious illnesses, and several respiratory conditions. [5]
The same review did not find any differences in effects of using these insulin analogues between adults and children. [6] Most oral anti-diabetic agents are contraindicated in pregnancy, in which case insulin is preferred. [7] Insulin is not administered by other routes, although this has been studied.
Victoza is FDA-approved to treat type 2 diabetes but is also sometimes prescribed off-label for weight loss. Saxenda is FDA-approved for weight management in people with obesity. 3.
The drugs were approved as additions to diet and exercise to improve blood sugar control in children aged 10 years and above with type 2 diabetes, the most common form of the disease. The ...
Most types of insulin therapy, an important part of diabetes treatment for many people, are given as daily injections to help manage blood sugar levels. Now, the maker of a once-weekly insulin ...
Alogliptin (FDA approved 2013 as Nesina/ Vipidia, marketed by Takeda Pharmaceutical Company) Trelagliptin (approved for use in Japan as Zafatek/ Wedica in 2015) Omarigliptin (MK-3102) (approved as Marizev in Japan in 2015, [ 12 ] developed by Merck & Co. ; research showed that omarigliptin can be used as once-weekly treatment and generally well ...
[32] [33] Liraglutide was approved by the FDA in 2019, for treatment of children ten years or older with type 2 diabetes, making it the first non-insulin drug approved to treat type 2 diabetes in children since metformin was approved in 2000. [34] Novo Nordisk made deals with generic manufacturers to enter the United States market in 2024.