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Pathology Outlines. Last author update: 28 May 2020; Author: Mikael Häggström, ... Histopathology of apocrine metaplasia of breast with typical features, H&E stain.
Accessory breasts, also known as polymastia, supernumerary breasts, or mammae erraticae, is the condition of having an additional breast. Extra breasts may appear with or without nipples or areolae. It is a condition and a form of atavism which is most prevalent in male humans, and often goes untreated as it is mostly harmless.
For breast pathology, also in distinguishing usual ductal hyperplasia (UDH) and papillary lesions (having a mosaic-like pattern) from ductal carcinoma in situ, which is usually negative. [1] Cyclin D1 and CK5/6 staining could be used in concert to distinguish between the diagnosis of papilloma (Cyclin D1 < 4.20%, CK 5/6 positive) or papillary ...
The Triple Nipple Club is a documentary shown on Channel 4 which explored the biological mystery of the supernumerary nipple. [9] First broadcast on 2 January 2008, it was directed and produced by Dan Louw and commissioned as part of Channel 4's First Cut series. [10]
The basal-like carcinoma is a recently proposed subtype of breast cancer defined by its gene expression and protein expression profile. [1]Breast cancer can be divided into five molecular subtypes, including luminal subtype A, luminal subtype B, normal breast-like subtype, HER-2 overexpression subtype, and basal-like subtype. [2]
Collagenous spherulosis is characterized by a tubular/cribriform architecture with intratubular eosinophilic material that classically is arranged like the spokes of a wheel ("radial spikes"). There is usually no mitotic activity, and two cells populations (epithelial & myoepithelial) are present, like in benign breast glands.
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Usual ductal hyperplasia (UDH) is a benign lesion of the breast wherein cells look very similar to normal. It is a spectrum of changes that can range from minimal stratification of cells to proliferations that are just short of atypical ductal hyperplasia .