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  2. Neurosteroid - Wikipedia

    en.wikipedia.org/wiki/Neurosteroid

    Neurosteroids are synthesized from cholesterol, which is converted into pregnenolone and then into all other endogenous steroids. Neurosteroids are produced in the brain after local synthesis or by conversion of peripherally-derived adrenal steroids or gonadal steroids. They accumulate especially in myelinating glial cells, from cholesterol or ...

  3. List of neurosteroids - Wikipedia

    en.wikipedia.org/wiki/List_of_neurosteroids

    This is a list of neurosteroids, or natural and synthetic steroids that are active on the mammalian nervous system through receptors other than steroid hormone receptors. It includes inhibitory , excitatory , and neurotrophic neurosteroids as well as pheromones and vomeropherines .

  4. Category:Neurosteroids - Wikipedia

    en.wikipedia.org/wiki/Category:Neurosteroids

    Main page; Contents; Current events; Random article; About Wikipedia; Contact us

  5. Pregnenolone - Wikipedia

    en.wikipedia.org/wiki/Pregnenolone

    Pregnenolone and its 3β-sulfate, pregnenolone sulfate, like dehydroepiandrosterone (DHEA), DHEA sulfate, and progesterone, belong to the group of neurosteroids that are found in high concentrations in certain areas of the brain, and are synthesized there. Neurosteroids affect synaptic functioning, are neuroprotective, and enhance myelinization.

  6. List of steroids - Wikipedia

    en.wikipedia.org/wiki/List_of_steroids

    List of neurosteroids – excitatory, inhibitory, mixed, neurotrophic, antineurotrophic, and other neurosteroids, as well as pheromones and pherines; List of steroidogenesis inhibitors – steroidogenesis inhibitors, or inhibitors of steroid biosynthesis and metabolism; As well as lists of steroid esters, including:

  7. Steroidogenic enzyme - Wikipedia

    en.wikipedia.org/wiki/Steroidogenic_enzyme

    Steroid desmolases. Cholesterol side-chain cleavage enzyme (20,22-desmolase) – steroid synthesis; 17,20-Lyase (17,20-desmolase) – androgen synthesis; Steroid hydroxylases. 11β-Hydroxylase – corticosteroid synthesis

  8. Progesterone - Wikipedia

    en.wikipedia.org/wiki/Progesterone

    Progesterone, like pregnenolone and dehydroepiandrosterone (DHEA), belongs to an important group of endogenous steroids called neurosteroids. It can be metabolized within all parts of the central nervous system. [77] Neurosteroids are neuromodulators, and are neuroprotective, neurogenic, and regulate neurotransmission and myelination. [78]

  9. Allopregnanolone - Wikipedia

    en.wikipedia.org/wiki/Allopregnanolone

    GABA A receptor-potentiating neurosteroids may preferentially target δ-subunit–containing GABA A receptors, and enhance both tonic and phasic inhibition mediated by GABA A receptors. [54] It is possible that neurosteroids like allopregnanolone may act on other targets , including membrane progesterone receptors, T-type voltage-gated calcium ...