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Cefpodoxime is an oral, third-generation cephalosporin antibiotic available in various generic preparations. It is active against both Gram-positive and Gram-negative organisms with notable exceptions including Pseudomonas aeruginosa , Enterococcus , and Bacteroides fragilis .
[44] [45] Among persons in the United States between 14 and 39 years of age, 46% of people with gonorrheal infection also have chlamydial infection. [46] For this reason, gonorrhea and chlamydia testing are often combined. [37] [47] [48] People diagnosed with gonorrhea infection have a fivefold increase risk of HIV transmission. [49]
The dosage may be increased up to 6 mg/kg/dose as needed, but not exceed the maximum dose for adults. For children with diseases other than above: 3 mg/kg/dose, 3 times a day after meals. The dosage may be adjusted according to the disease or the patients age and symptoms, but not exceed the maximum dose for adults.
Cefotaxime is an antibiotic used to treat several bacterial infections in humans, other animals, and plant tissue culture. [3] Specifically in humans it is used to treat joint infections, pelvic inflammatory disease, meningitis, pneumonia, urinary tract infections, sepsis, gonorrhea, and cellulitis. [3]
Gonorrhoea is a sexually transmitted infection (STI) caused by the bacterium Neisseria gonorrhoeae. [1]The World Health Organization (WHO) estimated that, in 2016, the global incidence rate was 20 per 1000 women and 26 per 1000 men, totaling 86.9 million new gonococcal infections among people between 15 and 49 years old.
Asymptomatic infection is common in both males and females. [8] [10] Untreated infection may spread to the rest of the body (disseminated gonorrhea infection), especially the joints (septic arthritis). Untreated infection in women may cause pelvic inflammatory disease and possible infertility due to the resulting scarring. [11]
Without treatment, about 10 percent of those with a chlamydial infection and 40 percent of those with a gonorrhea infection will develop PID. [ 2 ] [ 10 ] Risk factors are generally similar to those of sexually transmitted infections and include a high number of sexual partners and drug use . [ 2 ]
Cefadroxil is a first-generation cephalosporin antibacterial drug that is the para-hydroxy derivative of cephalexin, and is used similarly in the treatment of mild to moderate susceptible infections such as the bacterium Streptococcus pyogenes, causing the disease popularly called strep throat or streptococcal tonsillitis, urinary tract infection, reproductive tract infection, and skin infections.
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