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Eosinophilic ulcer of the tongue, [1] Riga–Fede disease, [1] Eosinophilic ulcer of the oral mucosa – H&E stain Eosinophilic ulcer of the oral mucosa (also known as traumatic eosinophilic granuloma [ 1 ] ) is a condition characterized by an ulcer with an indurated and elevated border. [ 2 ]
That is, the granulomas do not undergo the caseating ("cheese-like") necrosis typical of the granulomas of tuberculosis. There is disagreement as to whether OFG represents an early form of Crohn's disease or sarcoidosis, or whether it is a distinct, but similar clinical entity.
A pyogenic granuloma or lobular capillary hemangioma [3] is a vascular tumor that occurs on both mucosa and skin, and appears as an overgrowth of tissue due to irritation, physical trauma, or hormonal factors. [4] [5] It is often found to involve the gums, skin, or nasal septum, and has also been found far from the head, such as in the thigh. [6]
Granuloma annulare is a skin disease of unknown cause in which granulomas are found in the dermis of the skin, but it is not a true granuloma. Typically, a central zone of necrobiotic generation of collagen is seen, with surrounding inflammation and mucin deposition on pathology.
Human eosinophilic granuloma is characterized by abnormal proliferation of Langerhans cells (LCs). LCs are antigen-presenting cells derived from dendritic cells. In humans, eosinophilic granulomas are considered as a benign tumors that occurs mainly in children and adolescents. EG is a quite rare condition, and its incidence is higher in white ...
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
Chronic granulomatous disease (CGD), also known as Bridges–Good syndrome, chronic granulomatous disorder, and Quie syndrome, [1] is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds (most importantly the superoxide radical due to defective phagocyte NADPH oxidase) used to kill certain ingested pathogens. [2]
Childhood granulomatous periorificial dermatitis (CGPD) is a rare benign granulomatous skin disease of unknown cause. [1] The disorder was first described in 1970 by Gianotti in a case series of five children. [2] CGPD is more common in boys than girls. [3]