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  2. Pain management during childbirth - Wikipedia

    en.wikipedia.org/wiki/Pain_management_during...

    Perineal pain after childbirth has immediate and long-term negative effects for women and their babies. These effects can interfere with breastfeeding and the care of the infant. [24] The pain from injection sites and possible episiotomy is managed by the frequent assessment of the report of pain from the mother. Pain can come from possible ...

  3. Obstetric anesthesiology - Wikipedia

    en.wikipedia.org/wiki/Obstetric_anesthesiology

    Obstetric anesthesiologists typically serve as consultants to ob-gyn physicians and provide pain management for both complicated and uncomplicated pregnancies. [3] An obstetric anesthesiologist's practice may consist largely of managing pain during vaginal deliveries and administering anesthesia for cesarean sections; however, the scope is expanding to involve anesthesia for both maternal as ...

  4. Morphine - Wikipedia

    en.wikipedia.org/wiki/Morphine

    Morphine is used primarily to treat both acute and chronic severe pain.Its duration of analgesia is about three to seven hours. [12] [13] Side effects of nausea and constipation are rarely severe enough to warrant stopping treatment.

  5. Opioid - Wikipedia

    en.wikipedia.org/wiki/Opioid

    This requires them to increase their drug dosage to maintain the benefit, and that in turn also increases the unwanted side effects. [78] Long-term opioid use can cause opioid-induced hyperalgesia, which is a condition in which the patient has increased sensitivity to pain. [101] All of the opioids can cause side effects. [70]

  6. Patient-controlled analgesia - Wikipedia

    en.wikipedia.org/wiki/Patient-controlled_analgesia

    "A comparison of morphine administered by patient-controlled analgesia and regularly scheduled intramuscular injection in severe, postoperative pain". Journal of Pain and Symptom Management. 3 (1): 15– 22. doi: 10.1016/0885-3924(88)90133-9. PMID 3351344. Sechzer PH (1971). "Studies in pain with the analgesic-demand system". Anesthesia and ...

  7. μ-opioid receptor - Wikipedia

    en.wikipedia.org/wiki/Μ-opioid_receptor

    Miosis and reduced bowel motility tend to persist; little tolerance develops to these effects. [citation needed] The canonical MOR1 isoform is responsible for morphine-induced analgesia, whereas the alternatively spliced MOR1D isoform (through heterodimerization with the gastrin-releasing peptide receptor) is required for morphine-induced itching.

  8. Morphine - Wikipedia

    en.wikipedia.org/wiki/(+)-Morphine

    To the contrary, in rats, (+)-morphine acts as an antianalgesic and is approximately 71,000 times more potent as an antianalgesic than (−)-morphine is as an analgesic. [ 1 ] (+)-Morphine derives its antianalgesic effects by being a selective-agonist of the Toll-like receptor 4 (TLR4), which due to not binding to opioid receptors allows it to ...

  9. Epidural administration - Wikipedia

    en.wikipedia.org/wiki/Epidural_administration

    Medical intervention Epidural administration A freshly inserted lumbar epidural catheter. The site has been prepared with tincture of iodine, and the dressing has not yet been applied. Depth markings may be seen along the shaft of the catheter. ICD-9-CM 03.90 MeSH OPS-301 code 8-910 [edit on Wikidata] Epidural administration (from Ancient Greek ἐπί, "upon" + dura mater) is a method of ...