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Additionally, scientists discovered that participants who were heavy cannabis users also had reduced brain activity in certain areas of the brain, including the dorsolateral prefrontal cortex ...
In what the university calls the largest study of its kind, researchers used brain imaging technology to explore the effects of recent and lifetime cannabis use on brain function among more than ...
D’Souza added that cannabis use can have serious impacts on the developing brain because of its effects on the endocannabinoid system, a complex signaling system in the brain that marijuana targets.
The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Over time, the marijuana gateway hypothesis has been studied more and more. In one published study, the use of marijuana was shown not a reliable gateway cause of illicit drug use. [67] However, social factors and environment influence drug use and abuse, making the gateway effects of cannabis different for those in differing social circumstances.
While the most likely cellular targets and executors of the CB 2 receptor-mediated effects of endocannabinoids or synthetic agonists are the immune and immune-derived cells (e.g. leukocytes, various populations of T and B lymphocytes, monocytes/macrophages, dendritic cells, mast cells, microglia in the brain, Kupffer cells in the liver ...
A growing body of research and numerous anecdotal reports link cannabis with several health benefits.
Reports of the effects of cannabis on time perception can be found first in arts and literature, and then in medical reports and studies. Notable discussions of the effects occur in "Le Club des Hachichin" (1846), a work by French poet Théophile Gautier, and in Les Paradis Artificiels (1860), a work by Charles Baudelaire.