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AK-47, also known simply as AK, is a cannabis strain with high THC content. It is a hybrid strain of cannabis that is sativa-dominant; it mixes Colombian, Mexican, Thai, and Afghan strains. A strong and popular strain, it has won multiple cannabis industry awards. The plant genetics of AK-47 have been studied scientifically. [1] [2]
Tetrahydrocannabinolic acid (THCA, 2-COOH-THC; conjugate base tetrahydrocannabinolate) is a precursor of tetrahydrocannabinol (THC), an active component of cannabis. [1]THCA is found in variable quantities in fresh, undried cannabis, but is progressively decarboxylated to THC with drying, and especially under intense heating such as when cannabis is smoked or cooked into cannabis edibles.
Tetrahydrocannabinolic acid (THCA) synthase (full name Δ 1-tetrahydrocannabinolic acid synthase) is an enzyme responsible for catalyzing the formation of THCA from cannabigerolic acid (CBGA). THCA is the direct precursor of tetrahydrocannabinol (THC) , the principal psychoactive component of cannabis , which is produced from various strains of ...
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Heat is required to decarboxylate the non-psychoactive phytocannabinoid THCA to its psychoactive form, THC. Likewise, CBDA turns into CBD. From hemp plant material in an oven, cannabinoid concentration plots (time/temp) show THC: [16] STP 0 minutes 0.20mg/g; 140-160C 20 minutes 0.27mg/g; 140-160C 60 minutes 0.05-0.15mg/g
Strains used in medicine are often bred for high CBD content, and strains used for recreational purposes are usually bred for high THC content or for a specific chemical balance. Quantitative analysis of a plant's cannabinoid profile is often determined by gas chromatography (GC), or more reliably by gas chromatography combined with mass ...
However, cannabis does not naturally contain significant amounts of THC. Instead, tetrahydrocannabinolic acid (THCA) is found naturally in raw and live cannabis and is non-intoxicating. Over time, THCA slowly converts to THC through a process of decarboxylation over the course of roughly a year, but can be sped up with exposure to high ...
Also, due to their high potency, a very small dose of synthetic cannabinoids is used; moreover, synthetic cannabinoids are highly metabolized by the body, so the window to detect the parent drug (the synthetic cannabinoid itself) in blood and oral fluid is very small. [97]