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  2. Midazolam - Wikipedia

    en.wikipedia.org/wiki/Midazolam

    Onset of action: Within 5 min (IV), 15 min (IM), 20 min ... due to its long duration of action, ... the metabolism of midazolam leading to a reduced action.

  3. Diazepam - Wikipedia

    en.wikipedia.org/wiki/Diazepam

    The onset of action is one to five minutes for IV administration and 15–30 minutes for IM administration. The duration of diazepam's peak pharmacological effects is 15 minutes to one hour for both routes of administration. [68] The half-life of diazepam, in general, is 30–56 hours. [1]

  4. Palliative sedation - Wikipedia

    en.wikipedia.org/wiki/Palliative_sedation

    Among all benzodiazepine agents, midazolam (Versed) is the most frequently used medication for palliative sedation for its rapid onset and short duration of action. The main indications for midazolam in palliative sedation are to control delirium and alleviate breathing difficulties so as to minimize distress and prevent exacerbation of these ...

  5. Benzodiazepine use disorder - Wikipedia

    en.wikipedia.org/wiki/Benzodiazepine_use_disorder

    A short elimination half-life and a rapid onset of action are characteristics which increase the abuse potential of a benzodiazepines. [18] The following table provides the elimination half-life, approximate equivalent doses, speed of onset of action, and duration of behavioural effects. [32] [33]

  6. Propofol - Wikipedia

    en.wikipedia.org/wiki/Propofol

    To induce general anesthesia, propofol is the drug used almost exclusively, having largely replaced sodium thiopental. [13]It is often administered as part of an anesthesia maintenance technique called total intravenous anesthesia, using either manually programmed infusion pumps or computer-controlled infusion pumps in a process called target controlled infusion (TCI).

  7. Onset of action - Wikipedia

    en.wikipedia.org/wiki/Onset_of_action

    Onset of action is the duration of time it takes for a drug's effects to come to prominence upon administration. With oral administration , it typically ranges anywhere from 20 minutes to over an hour, depending on the drug in question.

  8. There's a New Over-the-Counter ED Drug. Should You Be ... - AOL

    www.aol.com/lifestyle/theres-over-counter-ed...

    MED3000’s 10-minute onset of action may be a game-changer when it comes to optimizing spontaneity.” ... Injections take less time to work, but they’re invasive and might deter men from using ...

  9. Flumazenil - Wikipedia

    en.wikipedia.org/wiki/Flumazenil

    The onset of action is rapid, and effects are usually seen within one to two minutes. The peak effect is seen at six to ten minutes. The recommended dose for adults is 200 μg every 1–2 minutes until the effect is seen, up to a maximum of 3 mg per hour.