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Azelaic acid (AzA ), or nonanedioic ... In topical pharmaceutical preparations and scientific research AzA is typically used in concentrations between 15% and 20% but ...
Azelaic acid (20%) is thought to decrease the activity of melanocytes. [ 3 ] [ 11 ] Tranexamic acid by mouth has shown to provide rapid and sustained lightening in melasma by decreasing melanogenesis in epidermal melanocytes.
Azelaic acid is effective for mild to moderate acne when applied topically at a 15–20% concentration. [ 67 ] [ 165 ] [ 166 ] [ 167 ] Treatment twice daily for six months is necessary, and is as effective as topical benzoyl peroxide 5%, isotretinoin 0.05%, and erythromycin 2%. [ 168 ]
A container with cream. Topical cream formulation is an emulsion semisolid dosage form that is used for skin external application. Most of the topical cream formulations contain more than 20 per cent of water and volatiles and/or less than 50 per cent of hydrocarbons, waxes, or polyethylene glycols as the vehicle for external skin application. [1]
There is an average 52% decrease in inflammatory acne lesions by week 12. [17]The combination is less effective than benzoyl peroxide/salicylic acid after short-term treatment of two to four weeks, but the two treatments showed similar effectiveness after ten to twelve weeks.
Adapalene Gel, sold in trade name Differin in China. Adapalene, sold under the brand name Differin among others, is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions. [6]
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