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Therefore, almost all new epilepsy drugs are initially approved only as adjunctive (add-on) therapies. Patients whose epilepsy is uncontrolled by their medication (i.e., it is refractory to treatment) are selected to see if supplementing the medication with the new drug leads to an improvement in seizure control.
Levetiracetam has not been found to be useful for treatment of neuropathic pain, [26] nor for treatment of essential tremors. [27] Levetiracetam has not been found to be useful for treating all developmental disorders within the autism spectrum; [28] [29] studies have only proven to be an effective treatment for partial, myoclonic, or tonic-clonic seizures associated with autism spectrum disorder.
A severe head injury, such as one sustained in a motor vehicle accident, fall, assault, or sports injury, can result in one or more seizures that can occur immediately after the fact or up to a significant amount of time later. [34] This could be hours, days, or even years following the injury.
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Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. [10] An epileptic seizure is the clinical manifestation of an abnormal, excessive, and synchronized electrical discharge in the neurons. [1]
Status epilepticus: Considered after failed treatment using a benzodiazepine due to slow onset of action. [16] Though phenytoin has been used to treat seizures in infants, as of 2023, its effectiveness in this age group has been evaluated in only one study. Due to the lack of a comparison group, the evidence is inconclusive. [17]
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Brian George worked in a hospital for more than 20 years wondering if a seizure would strike. Now, thanks to a laser ablation, he's seizure free. 'I wonder why I waited': Pharmacist still seizure ...