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Daily dose regimens are preferred to admission of large ... but there is an accord on the adult maximum of 100 μg/d (4000 IU/d). ... Calcium and Vitamin D3 are often ...
The Institute of Medicine in 2010 recommended a maximum uptake of vitamin D of 4000 IU/d, finding that the dose for lowest observed adverse effect level is 40,000 IU daily for at least 12 weeks, [25] and that there was a single case of toxicity above 10 000 IU after more than seven years of daily intake; this case of toxicity occurred in ...
Symptoms appear several months after excessive doses of vitamin D are administered. A mutation of the CYP24A1 gene can lead to a reduction in the degradation of vitamin D and thus to vitamin toxicity without high oral intake (see Vitamin D: Excess). Symptoms of vitamin D toxicity may include the following: [2] Dehydration; Vomiting; Diarrhea
The recommended maximum daily intake of sodium – the amount above which health problems appear – is 2,300 milligrams per day for adults, about 1 teaspoon of salt (5.9 g). The recommended adequate intake of sodium is 1,500 milligrams (3.9 g salt) per day, and people over 50 need even less."
In a study by De Niet et al., [72] 60 subjects with vitamin D deficiency were randomized to receive 2000 IU vitamin D3 daily or 50 000 IU monthly. They reported a similar efficacy of the two dosing frequencies, with the monthly dose providing more rapid normalization of vitamin D levels.
Flu A and flu B are the most common strains of the flu that circulate in humans. The U.S. is currently in the middle of flu season, with a high number of cases reported across the country.
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