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  2. Inbreeding - Wikipedia

    en.wikipedia.org/wiki/Inbreeding

    Cheetahs are another example of inbreeding. Thousands of years ago, the cheetah went through a population bottleneck that reduced its population dramatically so the animals that are alive today are all related to one another. A consequence from inbreeding for this species has been high juvenile mortality, low fecundity, and poor breeding ...

  3. Inbred strain - Wikipedia

    en.wikipedia.org/wiki/Inbred_strain

    "The period before World War I led to the initiation of inbreeding in rats by Dr Helen King in about 1909 and in mice by Dr C. C. Little in 1909. The latter project led to the development of the DBA strain of mice, now widely distributed as the two major sub-strains DBA/1 and DBA/2, which were separated in 1929-1930.

  4. Genetic purging - Wikipedia

    en.wikipedia.org/wiki/Genetic_purging

    Genetic purging is the increased pressure of natural selection against deleterious alleles prompted by inbreeding. [1]Purging occurs because deleterious alleles tend to be recessive, which means that they only express all their harmful effects when they are present in the two copies of the individual (i.e., in homozygosis).

  5. Zygosity - Wikipedia

    en.wikipedia.org/wiki/Zygosity

    The words homozygous, heterozygous, and hemizygous are used to describe the genotype of a diploid organism at a single locus on the DNA. Homozygous describes a genotype consisting of two identical alleles at a given locus, heterozygous describes a genotype consisting of two different alleles at a locus, hemizygous describes a genotype consisting of only a single copy of a particular gene in an ...

  6. F1 hybrid - Wikipedia

    en.wikipedia.org/wiki/F1_hybrid

    Two populations of breeding stock with desired characteristics are subjected to inbreeding until the homozygosity of the population exceeds a certain level, usually 90% or more. Typically, this requires more than 10 generations. Thereafter, the two strains must be crossed, while avoiding self-fertilization. Normally, this is done with plants by ...

  7. Inbreeding avoidance - Wikipedia

    en.wikipedia.org/wiki/Inbreeding_avoidance

    When two related individuals mate, the probability of deleterious recessive alleles pairing in the resulting offspring is higher as compared to when non-related individuals mate because of increased homozygosity. However, inbreeding also gives opportunity for genetic purging of deleterious alleles that otherwise would continue to exist in ...

  8. Inbreeding depression - Wikipedia

    en.wikipedia.org/wiki/Inbreeding_depression

    Inbreeding depression in Delphinium nelsonii. A. Overall fitness of progeny cohorts and the B. progeny lifespan were all lower when progeny were the result of crosses with pollen taken close to a receptor plant. [1] Inbreeding depression is the reduced biological fitness that has the potential to result from inbreeding (the breeding of related ...

  9. Allogamy - Wikipedia

    en.wikipedia.org/wiki/Allogamy

    After reaching homozygosity, the species develop homozygous balance and fail to exhibit inbreeding depression. Mechanisms that promote self-pollination include homogamy, bisexuality, cleistogamy, the position of anthers, and chasmogamy. [8] Allogamy promotes genetic diversity and reduces the risk of inbreeding depression.